| Identification | Back Directory | [Name]
(R)-(+)-Ketorolac | [CAS]
66635-93-6 | [Synonyms]
(R)-Ketorolac
(R)-(+)-Ketorolac
Ketorolac R-IsoMer
(R)-(+)-Ketorolac ISO 9001：2015 REACH
Ketorolac impurity 1/Ketorolac R-Isomer
(1R)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-, (1R)- | [Molecular Formula]
C15H13NO3 | [MOL File]
66635-93-6.mol | [Molecular Weight]
255.27 |
| Chemical Properties | Back Directory | [Melting point ]
163-170°C | [storage temp. ]
-20°C | [form ]
powder | [color ]
white to beige | [optical activity]
[α]/D +162 to +178°, c = 1 in methanol |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
(R)-Ketorolac is the R-enantiomer of Ketorolac. The (S)-enantiomer is about 60 times more potent than (R)-enantiomer. Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory. | [Definition]
ChEBI: A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has R configuration. Unlike the S-enantiomer, it does not exhibit COX1 and COX2 inhibition, but does exhibit analgesic activity. Racemic keto
olac, known simply as ketorolac, is used (mainly as a tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis. |
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