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ChemicalBook--->CAS DataBase List--->66536-81-0

66536-81-0

66536-81-0 Structure

66536-81-0 Structure
IdentificationBack Directory
[Name]

Uridine-5-oxyacetic acid methyl ester
[CAS]

66536-81-0
[Synonyms]

methyl uridin-5-yloxyacetate
Uridine-5-oxyacetic acid methyl ester
Uridine 5-oxyacetic acid methyl ester,RNA modified nucleoside mcmO5U
Acetic acid, [(1,2,3,4-tetrahydro-2,4-dioxo-1-β-D-ribofuranosyl-5-pyrimidinyl)oxy]-, methyl ester
[Molecular Formula]

C12H16N2O9
[MOL File]

66536-81-0.mol
[Molecular Weight]

332.26
Hazard InformationBack Directory
[Uses]

Uridine 5-oxyacetic acid methyl ester is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[Definition]

ChEBI: A methyl ester that is uridine which is substituted at position 5 on the uracil ring by a methoxycarbonylmethoxy group.
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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