Identification | Back Directory | [Name]
4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) | [CAS]
65996-58-9 | [Synonyms]
NSC 344522 9-deazaguanine 2-amino-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one 2-amino-1H-pyrrolo[3,2-d]pyrimidin-4(5H)-one 2-amino-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one 2-AMINO-3,5-DIHYDRO-PYRROLO[3,2-D]PYRIMIDIN-4-ONE
4H-Pyrrolo3,2-dpyrimidin-4-one, 2-amino-1,5-dihydro- 2-Amino-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one 2-amino-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-3,5-dihydro- 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) USP/EP/BP | [Molecular Formula]
C6H6N4O | [MDL Number]
MFCD09540493 | [MOL File]
65996-58-9.mol | [Molecular Weight]
150.14 |
Chemical Properties | Back Directory | [Melting point ]
>300 °C(Solv: water (7732-18-5)) | [density ]
1.87±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated) | [form ]
Solid | [pka]
10.85±0.20(Predicted) | [color ]
Beige |
Hazard Information | Back Directory | [Description]
9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; Kd = 160 nM).1 Inhibitors of PNP are used to control T cell proliferation, particularly in T cell cancers, autoimmune diseases, and tissue transplant rejection.2 | [Chemical Properties]
Beige Solid | [Uses]
A nucleoside analog as potent inhibitor of purine nucleoside phosphorylase. |
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