Identification | Back Directory | [Name]
ANGIOTENSINOGEN | [CAS]
64315-16-8 | [Synonyms]
RENIN SUBSTRATE ANGIOTENSINOGEN Angiotensinogen/CH8530 ANGIOTENSINOGEN (1-14) (HORSE) ANGIOTENSINOGEN (1-14), PORCINE angiotensinogen from hog plasma Tetradecapeptide renin substrate PREANGIOTENSINOGEN (1-14) (HORSE) Hypertensinogen (tetradecapeptide) ANGIOTENSINOGEN FROM PORCINE PLASMA ANGIOTENSINOGEN FRAGMENT 1-14 PORCINE ANGIOTENSINOGEN FROM HOG PLASMA, ~2 U/MG RENIN SUBSTRATE TETRADECAPEPTIDE PORCINE TETRADECAPEPTIDE RENIN SUBSTRATE (HORSE) Angiotensinogen (tetradecapeptide renin substrate) ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH Angiotensinogen from hog plasma, Hypertensinogen, Renin substrate | [Molecular Formula]
C85H123N21O20 | [MDL Number]
MFCD00133798 | [MOL File]
64315-16-8.mol | [Molecular Weight]
1759.01 |
Hazard Information | Back Directory | [Purification Methods]
This rennin substrate is purified 390-fold from the serum by chromatography on Blue Sepharose, phenyl sepharose, hydroxyapatite and finally by affinity chromatography on 5-hydroxytryptamine (5-HT) sepharose to which it specifically binds to the 5-HT. It is applied to the latter column in 50mM sodium phosphate at pH 7 and after washing, it is eluted by increasing the ionic strength with 100mM sodium phosphate buffer containing 250mM NaCl. The multiple forms are separated by SDSPAGE and have pI 4.40-4.82. [Campbell et al. Biochem J 243 121 1987.] |
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