| Identification | Back Directory | [Name]
Erythromycin stearate | [CAS]
643-22-1 | [Synonyms]
oe7
Wemid
Ethryn
ethril
erypar
eratrex
meberyt
Eryprim
Phizer-E
pfizer-e
qidmycin
dowmycine
Erythro S
abboticine
gallimycin
bristamycin
Stearate salt
Erythromycin s
sk-erythromycin
erythrocinstearate
Erythromycin stearat
ERYTHROMYCIN STEARATE
ERYTHROMYCIN STEARATE USP
ErythroMycin stearate API
Erythromycin, octadecanoate
erythromycin,stearate(salt)
erythromycinstearicacidsalt
ErythromycinStearate-Bp/Ep/Usp
Erythromycin Stearate (200 mg)
Erythromycin stearate (6CI, 7CI)
erythromycin,octadecanoate(salt)
Erythromycin, stearate (salt) (8CI)
ERYTHROMYCIN STEARATE USP(CRM STANDARD)
ERYTHROMYCIN STEARATE EPE(CRM STANDARD)
ErythromycinStearateErythromycinStearateBp/Usp
Stearic acid, compd. with erythromycin (1:1) (8CI)
ERYTHROMYCIN STEARATE ASSAY STANDARD BP(CRM STANDARD)
Octadecanoic acid, compd. with erythromycin (1:1) (9CI)
(3R,4S,5S,6R,7R,9R,11R,12R,13R,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione octadecanoic acid | [EINECS(EC#)]
211-396-1 | [Molecular Formula]
C55H103NO15 | [MDL Number]
MFCD00084690 | [MOL File]
643-22-1.mol | [Molecular Weight]
1018.4 |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
Macrodiles antibacterial | [Uses]
oil lubricant, plasticizer, solvent | [Uses]
Semi-synthetic macrolide antibiotic. Antibacterial | [General Description]
Fluffy colorless powder or fine white powder. | [Air & Water Reactions]
Insoluble in water. | [Reactivity Profile]
A base. Readily forms salts with acids. | [Fire Hazard]
Flash point data for Erythromycin stearate are not available; however, Erythromycin stearate is probably combustible. | [Originator]
Erythrocin Stearate,Abbott,US,1952 | [Definition]
ChEBI: Erythromycin stearate is an aminoglycoside. | [Manufacturing Process]
To a well-stirred solution of 3.18 grams (10.5 mmol) of stearoyl chloride and
1.24 grams (11.0 mmol) of 1-ethylpiperidine in 50 ml of methylene chloride is
added 7.20 grams (10.0 mmol) of erythromycin. After a short time complete
solution is obtained and stirring is then discontinued. The solution is allowed
to stand overnight. The solution is diluted to 250 ml by the addition of
methylene chloride and washed three times with 100 ml portions of water
followed by two washes with 5% sodium bicarbonate solution. The organic
layer is dried over anhydrous sodium sulfate and filtered, the solvent being
removed under diminished pressure. The product is dried to constant weightat room temperature in a vacuum desiccator. | [Brand name]
Bristamycin (Bristol-Myers Squibb); Erythrocin (Abbott). | [Therapeutic Function]
Antibacterial |
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