Identification | Back Directory | [Name]
10-formyl-5,8-dideazafolate | [CAS]
61038-31-1 | [Synonyms]
10-formyl-5,8-dideazafolate L-Glutamic acid, N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-quinazolinyl)methyl]formylamino]benzoyl]- (S)-2-(4-(N-((2-Amino-4-oxo-3,4-dihydroquinazolin-6-yl)methyl)formamido)benzamido)pentanedioic acid | [Molecular Formula]
C22H21N5O7 | [MOL File]
61038-31-1.mol | [Molecular Weight]
467.43 |
Hazard Information | Back Directory | [Biological Activity]
10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor[1]. | [References]
[1]. Reddy MR, et, al. Calculation of solvation and binding free energy differences for folate-based inhibitors of the enzyme thymidylate synthase. J. Am. Chem. Soc. 1992, 114, 26, 10117-10122. |
|
|