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ChemicalBook--->CAS DataBase List--->61038-31-1

61038-31-1

61038-31-1 Structure

61038-31-1 Structure
IdentificationBack Directory
[Name]

10-formyl-5,8-dideazafolate
[CAS]

61038-31-1
[Synonyms]

10-formyl-5,8-dideazafolate
L-Glutamic acid, N-[4-[[(2-amino-3,4-dihydro-4-oxo-6-quinazolinyl)methyl]formylamino]benzoyl]-
(S)-2-(4-(N-((2-Amino-4-oxo-3,4-dihydroquinazolin-6-yl)methyl)formamido)benzamido)pentanedioic acid
[Molecular Formula]

C22H21N5O7
[MOL File]

61038-31-1.mol
[Molecular Weight]

467.43
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 50 mg/mL (106.97 mM; Need ultrasonic)
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Biological Activity]

10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor[1].
[References]

[1]. Reddy MR, et, al. Calculation of solvation and binding free energy differences for folate-based inhibitors of the enzyme thymidylate synthase. J. Am. Chem. Soc. 1992, 114, 26, 10117-10122.
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