| Identification | Back Directory | [Name]
2-NITROFURAN | [CAS]
609-39-2 | [Synonyms]
NSC 59983
Nitrofuran
2-NITROFURAN
2-nitro-fura
5-Nitrofuran
2-Nitrofurane
Furan, 2-nitro- | [Molecular Formula]
C4H3NO3 | [MDL Number]
MFCD00013442 | [MOL File]
609-39-2.mol | [Molecular Weight]
113.07 |
| Chemical Properties | Back Directory | [Appearance]
solid | [Melting point ]
29-33 °C(lit.)
| [Boiling point ]
84 °C13 mm Hg(lit.)
| [density ]
1.5808 (rough estimate) | [refractive index ]
1.4543 (estimate) | [Fp ]
191 °F
| [storage temp. ]
2-8°C | [solubility ]
Chloroform, Methanol | [form ]
Solid | [color ]
Clear Colorless to Off-White | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [CAS DataBase Reference]
609-39-2 |
| Hazard Information | Back Directory | [Chemical Properties]
solid | [Uses]
A minor antimicrobial used in veterinary medicine. | [Definition]
ChEBI: 2-nitrofuran is a member of furans and a C-nitro compound. | [Environmental Fate]
2-Nitrofuran is a yellow crystalline solid with molecular weight
of 113.07152 g mol-1. The boiling point of 2-nitrofuran is
84 ℃ at 17 hPa and the melting point is 29–33 ℃. It is
a flammable solid. Its flash point is 88 ℃ (closed cup). Vapor
pressure is 0.398mmHg at 25 ℃. This compound is soluble in
H2O and ethanol. Its density is 1.344 g cm-3.
The partition behavior of 2-nitrofuran in water, sediment,
and soil is 0.8. No data are available on its environmental
persistency (degradation/speciation), long-range transport,
bioaccumulation, and biomagnification. This chemical is
stable but it is incompatible with strong oxidizing agents. | [Toxicity evaluation]
2-Nitrofuran reacts with DNA to form complexes, induces
interstrand cross-links, produces alkali-labile lesions, and
interferes with nucleic acid synthesis. Removal of the nitro
group decreases the mutagenic activity. |
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