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ChemicalBook--->CAS DataBase List--->60482-95-3

60482-95-3

60482-95-3 Structure

60482-95-3 Structure
IdentificationBack Directory
[Name]

NEUROTENSIN (8-13)
[CAS]

60482-95-3
[Synonyms]

RRPYIL
NEUROTENSIN (8-13)
Neurotensin(8-13)【ox】
Neurotensin(8-13)(3TFA)
ARG-ARG-PRO-TYR-ILE-LEU
NEUROTENSIN, FRAGMENT 8-13
H-ARG-ARG-PRO-TYR-ILE-LEU-OH
neurotensin fragment 8-13 acetate
ARG-ARG-PRO-TYR-ILE-LEU ACETATE SALT
AC-ARG-ARG-PRO-TYR-ILE-LEU: AC-RRPYIL
L-Arg-L-Arg-L-Pro-L-Tyr-L-Ile-L-Leu-OH
NEUROTENSIN FRAGMENT 8-13 ACETATE SALT
Neurotensin (8-13) H-Arg-Arg-Pro-Tyr-Ile-Leu-OH
Neurotensin Fragment 8-13 acetate salt >=97% (HPLC)
L-Leucine, L-arginyl-L-arginyl-L-prolyl-L-tyrosyl-L-isoleucyl-
[Molecular Formula]

C38H64N12O8
[MDL Number]

MFCD00076686
[MOL File]

60482-95-3.mol
[Molecular Weight]

816.99
Chemical PropertiesBack Directory
[density ]

1.40±0.1 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Sealed in dry,Store in freezer, under -20°C
[form ]

Solid
[pka]

3.41±0.10(Predicted)
[color ]

White to off-white
[Water Solubility ]

Water: 50 mg/mL (61.20 mM)
[Sequence]

H-Arg-Arg-Pro-Tyr-Ile-Leu-OH
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
[WGK Germany ]

3
Hazard InformationBack Directory
[Biological Activity]

Neurotensin (8-13) is the active fragment of neurotensin, Neurotensin (8-13) reduces cell surface NT1 receptor (NTR1) density.
[in vitro]

Receptor internalization induced by Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. The receptor downregulation in response to high extracellular concentrations of the peptide has been described for Neurotensin (NT ) in HT-29 cells and in rat primary cultured neurons. Reappearance of the receptors on the cell surface is also different.

[target]

NTR1

[storage]

Store at -20°C
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