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ChemicalBook--->CAS DataBase List--->598-72-1

598-72-1

598-72-1 Structure

598-72-1 Structure
IdentificationBack Directory
[Name]

DL-2-Bromopropionic
[CAS]

598-72-1
[Synonyms]

2-broMide
2-Bromopropion
2-BROMOPROPANAMIDE
2-BroMine Propionic
DL-2-Bromopropionic
RARECHEM AL BO 1266
2-bromo-propanoicaci
2-bromopropanoicacid
2-bromo-propionicaci
DL-Bromopropanoicacid
2-bromo-Propanoicacid
2-BROMOPROPIONIC ACID
A-BROMOPROPIONIC ACID
Propanoicacid,2-bromo-
Propionic acid, 2-bromo-
Propanoic acid, 2-bromo-
2-Bromopropionicacid,98%
(S)-2-BROMOPROPANOIC ACID
YA10760700MB 2-BroMopropi
ALPHA-BROMOPROPIONIC ACID
D,L-2-BROMOPROPIONIC ACID
(R,S)-2-BROMOPROPIONICACID
(+/-)-2-BROMOPROPIONIC ACID
2-BROMOPROPIONIC ACID, 99+%
DL-2-Bromopropionic acid, 99+%
2-bromopropionic acid solution
2-BROMOPROPIONIC ACID, 1000MG,NEAT
Salicylamide O-Acetate Sodium Salt
2-BROMOPROPIONIC ACID FOR SYNTHESIS
DL-2-BroMopropionic acid, 99+% 250GR
2-BROMOPROPIONIC ACID, 1X1ML, MTBE 1000U G/ML
(+/-)-2-Bromopropionic acid purum, >=98.0% (GC)
(±)-2-Bromopropionic acid DL-2-Bromopropionic acid
[EINECS(EC#)]

209-947-6
[Molecular Formula]

C3H5BrO2
[MDL Number]

MFCD00004211
[MOL File]

598-72-1.mol
[Molecular Weight]

152.97
Chemical PropertiesBack Directory
[Appearance]

clear colorless to yellowish liquid after melting
[Melting point ]

25.7°C
[Boiling point ]

203 °C(lit.)
[density ]

1.7 g/mL at 25 °C(lit.)
[refractive index ]

n20/D 1.475(lit.)
[Fp ]

212 °F
[storage temp. ]

room temp
[form ]

Liquid After Melting
[pka]

pK1: 2.971 (25°C)
[color ]

Clear colorless to yellow
[Specific Gravity]

1.7
[Water Solubility ]

soluble
[BRN ]

605451
[Dielectric constant]

11.0
[NIST Chemistry Reference]

2-Bromopropanoic acid(598-72-1)
[EPA Substance Registry System]

Propanoic acid, 2-bromo-(598-72-1)
Hazard InformationBack Directory
[Chemical Properties]

clear colorless to yellowish liquid after melting
[Uses]

It is employed as pharmaceutical and agrochemical intermediate. It is used as an alkylation agent for mercaptans and other sulfur containing compounds.
[Application]

2-bromopropionic acid is an organic synthesis intermediate, used in the production of herbicides quizalofop-ethyl, napropamide, fenthiaprop and fungicides metalaxyl, benalaxyl, procymidone, etc., used in the synthesis of pharmaceutical intermediates body alanine.
[Preparation]

2-Bromopropionic acid is obtained by bromination of propionic acid. Add propionic acid and phosphorus trichloride to the reaction kettle, keep the temperature at 80°C, slowly add bromine to the reaction solution dropwise, and heat up to 85°C after the addition of bromine, and raise the temperature to 100°C when the color of bromine disappears completely, it takes about 2~3h, and then the bromine and hydrobromic acid are recovered under reduced pressure, and then the finished product is obtained by distillation under reduced pressure.
[Synthesis Reference(s)]

Tetrahedron Letters, 13, p. 4067, 1972 DOI: 10.1016/S0040-4039(01)94239-X
Safety DataBack Directory
[Hazard Codes ]

C,Xi,F
[Risk Statements ]

22-34-40-36/37/38-38-11
[Safety Statements ]

26-36/37/39-45-36-16-24-9
[RIDADR ]

UN 3265 8/PG 2
[WGK Germany ]

3
[RTECS ]

UA2451715
[TSCA ]

Yes
[HazardClass ]

8
[PackingGroup ]

II
[HS Code ]

29159080
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Phosphorus trichloride-->Propionic acid
[Preparation Products]

L-Alanine-->NAPROANILIDE-->2-Phenoxypropionic acid-->2-(methylthio)propionic acid-->1,1-Dibromoethane-->(R)-(+)-2-BROMOPROPIONIC ACID-->2-methoxypropionic acid-->(S)-(-)-2-BROMOPROPIONIC ACID-->Trimethylsulfonium bromide-->Ethyl 2-aminopropanoate hydrochloride-->Potassium lactate-->2-(4-BROMOPHENOXY)PROPANOIC ACID
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

DL-2-Bromopropionic (598-72-1).msds
Spectrum DetailBack Directory
[Spectrum Detail]

2-Bromopropionic acid(598-72-1)MS
2-Bromopropionic acid(598-72-1)1HNMR
2-Bromopropionic acid(598-72-1)13CNMR
2-Bromopropionic acid(598-72-1)IR1
2-Bromopropionic acid(598-72-1)IR2
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