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ChemicalBook--->CAS DataBase List--->581065-94-3

581065-94-3

581065-94-3 Structure

581065-94-3 Structure
IdentificationBack Directory
[Name]

Tos-PEG5 t-butyl ester
[CAS]

581065-94-3
[Synonyms]

Tos-PEG5-Boc
Tos-PEG5-COOtBu
CAS_581065-94-3
Tos-PEG4-COOtBu
Tos-PEG5 t-butyl ester
Tos-PEG5 tert-Butyl Ester
tert-Butyl 1-(Tosyloxy)-3,6,9,12-tetraoxapentadecan-15-oate
1-(Tosyloxy)-3,6,9,12-tetraoxapentadecan-15-oic Acid tert-Butyl Ester
tert-butyl 3-[2-(2-{2-[2-(toluene-4-sulfonyloxy)-ethoxy]ethoxy}ethoxy)ethoxy]propionate
4,7,10,13-Tetraoxapentadecanoic acid, 15-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
[Molecular Formula]

C22H36O9S
[MDL Number]

MFCD22574810
[MOL File]

581065-94-3.mol
[Molecular Weight]

476.58
Chemical PropertiesBack Directory
[Boiling point ]

560.5±50.0 °C(Predicted)
[density ]

1.151±0.06 g/cm3(Predicted)
[refractive index ]

1.49
[form ]

clear liquid
[color ]

Colorless to Light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319
[Precautionary statements ]

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
[HS Code ]

2918.99.4700
Hazard InformationBack Directory
[Description]

Tos-PEG5-t-butyl ester is a PEG linker containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
[Uses]

This compound is used in preparation of taxanes. Taxanes have improved its toxicity and solubility in aqueous solution compared to paciitaxel.
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