| Identification | Back Directory | [Name]
7BETA-HYDROXYCHOLESTEROL | [CAS]
566-27-8 | [Synonyms]
7B-hydroxycholesterol
7β-hydroxycholesterol
cholest-5-en-3,7-diol
7β-hydroxy Cholesterol
7β-Hydrloxy Cholestero
Cholest-5-ene-3,7-diol
5-cholestene-3β,7β-diol
Cholesterol Impurity 29
7BETA-HYDROXYCHOLESTEROL
7-Hydroxycholest-5-en-3-ol
(3,7)-Cholest-5-ene-3,7-diol
5-CHOLESTENE-3BETA,7BETA-DIOL
5-CHOLESTEN-3-BETA, 7-BETA-DIOL
cholest-5-ene-3-beta,7-beta-diol
Cholest-5-ene-3,7-diol, (3b,7b)-
3BETA,7BETA-DIHYDROXY-5-CHOLESTENE
7β-Hydroxycholesterol (not deuterated)
7|beta|-Hydroxycholesterol (not deuterated)
(7R,8S,9S,10R,13R,14S,17R)-17-[(1R)-1,5-dimethylhexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
(7R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
(3S,7R,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
(3S,7R,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol | [Molecular Formula]
C27H46O2 | [MDL Number]
MFCD00058406 | [MOL File]
566-27-8.mol | [Molecular Weight]
402.65 |
| Chemical Properties | Back Directory | [Melting point ]
165-167?C | [Boiling point ]
515.3±38.0 °C(Predicted) | [density ]
1.03±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C Freezer | [solubility ]
Chloroform (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
14.11±0.70(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Uses]
A metabolite of Cholesterol. Its membrane organizing properties could have implications in Altzheimer’s disease. | [Definition]
ChEBI: 7beta-hydroxycholesterol is an oxysterol and a 7beta-hydroxy steroid. It is functionally related to a cholesterol. | [Biological Activity]
7β-Hydroxycholesterol is an oxysterolthe enzymatic or non-enzymatic product of cholesterol oxidation. Oxysterols are cytotoxic and induce death in monocytessmooth muscle cells and endothelial cells. The mechanism of apoptosis induced by oxysterols may involve caspases or DNA fragmentation. Increased levels of 7β-Hydroxycholesterol correlates with increased risk of cardiovascular diseases including atherosclerosis. |
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