| Identification | Back Directory | [Name]
2-HYDROXYOLEICACID | [CAS]
56472-29-8 | [Synonyms]
2OHOA
Minerval
Acumapimod
-d17 Minerva-d17l
2-HYDROXYOLEICACID
α-Hydroxyoleic Acid
α-Hydroxyoleic Acid-d17
(Z)-2-Hydroxyoctadec-9-enoic acid
cis-2-Hydroxy-9-octadecenoic Acid
(9Z)-2-Hydroxy-9-octadecenoic Acid
(Z)-2-Hydroxyoctadec-9-enoic Acid-d17
cis-2-Hydroxy-9-octadecenoic Acid-d17
(9Z)-2-Hydroxy-9-octadecenoic Acid-d17
9-Octadecenoic acid, 2-hydroxy-, (9Z)-
2-Hydroxy Oleic Acid (Mixture of Z and E IsoMers)
2-Hydroxy Oleic Acid-d17 (Mixture of Z and E IsoMers) | [Molecular Formula]
C18H34O3 | [MDL Number]
MFCD07778553 | [MOL File]
56472-29-8.mol | [Molecular Weight]
298.46 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White to Pale Beige Solid | [Uses]
An oleic acid synthetic analog that is an effective non-toxic anticancer drug with a wide spectrum against different types of cancer. An antihypertensive. | [Definition]
ChEBI: 2-hydroxyoleic acid is a 2-hydroxy fatty acid that is oleic acid which carries a hydroxy group at position 2. It is an orally bioavailable synthetic hydroxylated fatty acid which modulates the lipid content of cancer cell membranes and induces cell cycle arrest and apoptosis in several cancer cell lines. It has a role as an antineoplastic agent, an apoptosis inducer and an antihypertensive agent. It is a 2-hydroxy fatty acid, a long-chain fatty acid and a hydroxy monounsaturated fatty acid. It is functionally related to an oleic acid. It is a conjugate acid of a 2-hydroxyoleate. | [Biochem/physiol Actions]
2-Hydroxy oleic acid (2OHOA) is a derivative of oleic acid. It plays a role in membrane organization, alterations in?membrane fluidity, an increase of the tendency to form non-lamellar structures, and remodeling of microdomains by interacting with the lipids in membranes of pathological cells. | [storage]
4°C, protect from light |
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