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ChemicalBook--->CAS DataBase List--->56083-03-5

56083-03-5

56083-03-5 Structure

56083-03-5 Structure
IdentificationBack Directory
[Name]

IsobavachroMene
[CAS]

56083-03-5
[Synonyms]

IsobavachroMene
4-Hydroxylonchocarpin
4-Hydroxylonchocarpin/Isobavachromene
(2E)-1-(5-Hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-hydroxyphenyl)-2-propen-1-one
2-Propen-1-one,1-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-hydroxyphenyl)-,(E)-
2-Propen-1-one, 1-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl)-3-(4-hydroxyphenyl)-, (2E)-
[Molecular Formula]

C20H18O4
[MDL Number]

MFCD21333543
[MOL File]

56083-03-5.mol
[Molecular Weight]

322.35
Chemical PropertiesBack Directory
[Melting point ]

203-204℃
[Boiling point ]

535.1±50.0 °C(Predicted)
[density ]

1.257±0.06 g/cm3(Predicted)
[storage temp. ]

4°C, protect from light
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

7.25±0.40(Predicted)
[color ]

Yellow to orange
Hazard InformationBack Directory
[Uses]

4-Hydroxylonchocarpin is a chalcone compound from an extract of Psoralea corylifolia. 4-Hydroxylonchocarpin increases phosphorylation of p38 MAPK, JNK and ERK. 4-Hydroxylonchocarpin has diverse pharmacological activities, including antibacterial, antifungal, anticancer, antireverse transcriptase, antitubercular, antimalarial, anti-inflammatory and antioxidant activities[1].
[References]

[1] Lim J, et al. Antimelanogenic effect of 4-hydroxylonchocarpin through the inhibition of tyrosinase-related proteins and MAPK phosphatase. Exp Dermatol. 2016 Jul;25(7):574-6. DOI:10.1111/exd.13004
Spectrum DetailBack Directory
[Spectrum Detail]

IsobavachroMene(56083-03-5)1HNMR
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