Identification | Back Directory | [Name]
Dihydrostreptomycin sulfate | [CAS]
5490-27-7 | [Synonyms]
Sol-Mycin didromycin didromycine panstreptin Double-Mycin StreptoMagna Sesquisulfate Prestwick_173 Dihydrostreptomycin sulfate dihydrostreptomycin solution dihydrostreptomycin3/2sulfate Dihydrostreptomycin sulfate CRS DIHYDROSTREPTOMYCINSULPHATE(INJ.) DIHYDROSTREPTOMYCINSULPHATE(ORAL) Dihydrostreptomycin sulfate ( 2:3 ) Dihydrostreptomycin Sulfate Sterile Dihydrostreptomycin Sesquisulfate D9 Dihydrostreptomycin Sulfate (200 mg) dihydro-streptomycisulfate(2:3)(salt) Dihydrostreptomycin sulfate USP/EP/BP DIHYDROSTREPTOMYCIN STANDARD SOLUTION* DIHYDROSTREPTOMYCIN SULFATE CRYSTALLINE DIHYDROSTREPTOMYCIN SESQUISULFATE HYDRATE Dihydrostreptomycin sulfate solution,100ppm Dihydrostreptomycin sulfate solution,1000ppm DIHYDROSTREPTOMYCIN SESQUISULFATE TRIHYDRATE Dihydrostreptomycin Sulphate For Veterinary Use Dihydrostreptomycin sesquisulfate Solution, 100ppm DihydrostreptoMycin sulphate for veterinary use COS DIHYDROSTREPTOMYCIN SESQUISULFATE CELL*C ULTURE TEST Dihydrostreptomycin sulfate Solution in Water, 100μg/mL DIHYDROSTREPTOMYCIN SULFATE CELL CULTURE REAGENT CRYSTALLINE n’-bis(aminoiminomethyl)--3-c-(hydroxymethyl)-alpha-l-lyxofuranosyl-(1-4)- d-streptamine,o-2-deoxy-2-(methylamino)-alpha-l-glucopyranosyl-(1.fwdarw.2)-o -5-deoxy-3-c-(hydroxymethyl)-alpha-l-lyxofuranosyl-(1.fwdarw.4)-n,n’-bis(amino O-2-deoxy-2-(MethylaMino)-α-L-glucopyranosyl-(1→2)-O-5-deoxy-3-C-(hydroxyMethyl)-α-L-lyxofuranosyl-(1→4)-N1,N3-bis(aMinoiMinoMethyl)-D-StreptaMine Sulfate D-Streptamine, O-2-deoxy-2-(methylamino)-.alpha.-L-glucopyranosyl-(1?2)-O-5-deoxy-3-C-(hydroxymethyl)-.alpha.-L-lyxofuranosyl-(1?4)-N,N-bis(aminoiminomethyl)-, sulfate (2:3) (salt) 1,1'-((1R,2R,3S,4R,5R,6S)-4-(((2R,3R,4R,5S)-3-(((2S,3S,4S,5R,6S)-4,5-Dihydroxy-6-(hydroxymethyl)-3-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-4-hydroxy-4-(hydroxymethyl)-5-methyltetrahydrofuran-2-yl)oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl)diguanidine sesquisulfate | [EINECS(EC#)]
226-823-7 | [Molecular Formula]
C40H86N14O37S3 | [MDL Number]
MFCD00167162 | [MOL File]
5490-27-7.mol | [Molecular Weight]
1451.38 |
Hazard Information | Back Directory | [Chemical Properties]
White Solid | [Originator]
Dihydrostrepto,MSD ,US,1948 | [Uses]
antibacterial, tuberculostatic | [Uses]
As a derivative of Streptomycin (S687500) with antimicrobial activity, Dihydrostreptomycin sulfate is used in veterinary medicine to treat bovine infection and also as an effective antibiotic to control pests found in crops.
| [Manufacturing Process]
Dihydrostreptomycin sulfate may be prepared from streptomycin sulfate by
catalytic hydrogenation (Merck, Pfizer, Cyanamid), electrolytic reduction
(Schenley, Olin Mathieson), or by sodium borohydride reduction (Bristol), or
by isolation from a fermentation process (Takeda). | [Therapeutic Function]
Antibiotic | [Purification Methods]
It crystallises from H2O, MeOH, n-BuOH or methyl ethyl ketone. The crystals are not hygroscopic like the amorphous powder; however, both forms are soluble in H2O but the amorphous solid is about 10 times more soluble than the crystals. The free base also crystallises from H2O/Me2CO and has [] D -92o (aqueous solution pH 7.0). [Solomons & Regina Science 109 515 1949, Wolf et al. Science 109 515 1949, McGilveray & Rinehart J Am Chem Soc 87 4003 1956]. [Beilstein 18 III/IV 7538.] |
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