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ChemicalBook--->CAS DataBase List--->54164-50-0

54164-50-0

54164-50-0 Structure

54164-50-0 Structure
IdentificationBack Directory
[Name]

NERVONIC CERAMIDE
[CAS]

54164-50-0
[Synonyms]

NERVONIC CERAMIDE
NERVONYL CERAMIDE
15-TETRACOSENAMIDE
NERVONYL-D-SPHINGOSINE
N-nervonoyl-D-sphingosine
N-15Z-TETRACOSENOYLSPHINGOSINE
C24:1 Ceramide (d18:1/24:1(15Z))
N-[CIS-TETRACOSENOYL]-D-SPHINGOSINE
N-cis-15-Tetracosenoyl-C18-sphingosine
N-(cis-15-Tetracosenoyl)-D-sphingosine
N-nervonoyl-D-sphingosine semisynthetic
Nervonyl Ceramide, N-[cis-Tetracosenoyl]-D-sphingosine
D-erythro-1,3-Dihydroxy-2-(cis-15-tetra- cosenoylaMido)-trans-4-octadecene
(15Z)-N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxyMethyl)-3-heptadecen-1-yl]-15-tetracosenaMide
[Molecular Formula]

C42H81NO3
[MDL Number]

MFCD00057779
[MOL File]

54164-50-0.mol
[Molecular Weight]

648.1
Chemical PropertiesBack Directory
[Appearance]

Off-White Solid
[Melting point ]

80-82°C
[storage temp. ]

-20°C
[solubility ]

Chloroform (Slightly), Methanol (Slightly, Heated)
[form ]

Solid
[color ]

Off-White
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Uses]

N-Nervonoyl-D-sphingosine is a sphingolipid. Sphingolipids (SLs) act as signaling molecules and as structural components in both neuronal cells and myelin.
[Definition]

ChEBI: N-(15Z)-tetracosenoylsphingosine is an N-tetracosenoylsphingosine in which the double bond in the ceramide acyl group is located at position 15 (the Z-geoisomer. It has a role as a mouse metabolite. It is a N-tetracosenoylsphingosine and a Cer(d42:2). It is functionally related to a (15Z)-tetracosenoic acid.
[Biological Activity]

Ceramide (d18:1/24:1[15Z]) levels are elevated inprimary open angle glaucoma (POAG). It is a biomarker for the human arterial tissue and plasma major adverse cardiac and cerebrovascular events (MACE). In generalceramides are key second messengers in sphingomyelin pathway and modulate the pathophysiology of metabolic diseases.
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