Identification | Back Directory | [Name]
Cytochalasin H | [CAS]
53760-19-3 | [Synonyms]
paspalin Nsc305222 Aids031241 paspalinpi Aids-031241 Paspalin P1 CYTOCHALASIN H 19-triene-1-one kodocytochalasin-1 Cytochalasin H(CytH) Cytochalasin H (>90%) Cytochalasin H USP/EP/BP cytochalasinhfromphomopsissp. 17-Deoxo-21-acetylzygosporin D cytochalasin H from A phomopsis species (7s,13e,16s,18s,19e,21r)-methyl-10-phenyl Kodocytochalasin 1, Paspalin P1, 17-Deoxo-21-acetylzygosporin D 21-acetoxy-7,18-dihydroxy-16,18-dimethyl-10-phenyl-(11)cytochalasa-6(12),13, (11)cytochalasa-6(12),13,19-trien-1-one,21-(acetyloxy)-7,18-dihydroxy-16,18-di PASPALIN P1; KODOCYTOCHALASIN 1; CYTOCHALASIN O; NSC305222; 17-DEOXO-21-ACETYLZYGOSPORIN D (7S,13E,16S,18R,19E,21R)-21-Acetyloxy-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-trien-1-one (16-Benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-18-oxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl) acetate Acetic acid 16-benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylene-18-oxo-17-aza-tricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl ester 1H-Cycloundec[d]isoindol-1-one, 15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)- | [Molecular Formula]
C30H39NO5 | [MDL Number]
MFCD00010539 | [MOL File]
53760-19-3.mol | [Molecular Weight]
493.63 |
Chemical Properties | Back Directory | [Melting point ]
252-258 °C | [Boiling point ]
587°C (rough estimate) | [density ]
1.1369 (rough estimate) | [refractive index ]
1.6310 (estimate) | [storage temp. ]
2-8°C | [solubility ]
chloroform: 10 mg/mL, clear, colorless | [form ]
A lyophilisate | [pka]
13.88±0.70(Predicted) | [color ]
Long needles from CHCl3/Et2O | [BRN ]
1632647 | [InChIKey]
NAEWXXDGBKTIMN-QHDZSFFESA-N | [LogP]
4.758 (est) |
Hazard Information | Back Directory | [Uses]
Cytochalasin H is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, resulting in pronounced morphogenic changes in animals and plants. In vitro, cytochalasin H exhibits antibacterial, antifungal, nematocidal and antitumour activity. | [Safety Profile]
Poison by intravenous and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. | [storage]
+4°C |
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