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ChemicalBook--->CAS DataBase List--->53760-19-3

53760-19-3

53760-19-3 Structure

53760-19-3 Structure
IdentificationBack Directory
[Name]

Cytochalasin H
[CAS]

53760-19-3
[Synonyms]

paspalin
Nsc305222
Aids031241
paspalinpi
Aids-031241
Paspalin P1
CYTOCHALASIN H
19-triene-1-one
kodocytochalasin-1
Cytochalasin H(CytH)
Cytochalasin H (>90%)
Cytochalasin H USP/EP/BP
cytochalasinhfromphomopsissp.
17-Deoxo-21-acetylzygosporin D
cytochalasin H from A phomopsis species
(7s,13e,16s,18s,19e,21r)-methyl-10-phenyl
Kodocytochalasin 1, Paspalin P1, 17-Deoxo-21-acetylzygosporin D
21-acetoxy-7,18-dihydroxy-16,18-dimethyl-10-phenyl-(11)cytochalasa-6(12),13,
(11)cytochalasa-6(12),13,19-trien-1-one,21-(acetyloxy)-7,18-dihydroxy-16,18-di
PASPALIN P1; KODOCYTOCHALASIN 1; CYTOCHALASIN O; NSC305222; 17-DEOXO-21-ACETYLZYGOSPORIN D
(7S,13E,16S,18R,19E,21R)-21-Acetyloxy-7,18-dihydroxy-16,18-dimethyl-10-phenyl[11]cytochalasa-6(12),13,19-trien-1-one
(16-Benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylidene-18-oxo-17-azatricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl) acetate
Acetic acid 16-benzyl-5,12-dihydroxy-5,7,14-trimethyl-13-methylene-18-oxo-17-aza-tricyclo[9.7.0.01,15]octadeca-3,9-dien-2-yl ester
1H-Cycloundec[d]isoindol-1-one, 15-(acetyloxy)-2,3,3a,4,5,6,6a,9,10,11,12,15-dodecahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, (3S,3aR,4S,6S,6aR,7E,10S,12R,13E,15R,15aR)-
[Molecular Formula]

C30H39NO5
[MDL Number]

MFCD00010539
[MOL File]

53760-19-3.mol
[Molecular Weight]

493.63
Chemical PropertiesBack Directory
[Melting point ]

252-258 °C
[Boiling point ]

587°C (rough estimate)
[density ]

1.1369 (rough estimate)
[refractive index ]

1.6310 (estimate)
[storage temp. ]

2-8°C
[solubility ]

chloroform: 10 mg/mL, clear, colorless
[form ]

A lyophilisate
[pka]

13.88±0.70(Predicted)
[color ]

Long needles from CHCl3/Et2O
[BRN ]

1632647
[InChIKey]

NAEWXXDGBKTIMN-QHDZSFFESA-N
[LogP]

4.758 (est)
Safety DataBack Directory
[Hazard Codes ]

T+
[Risk Statements ]

26/27/28-63
[Safety Statements ]

28-36/37-45
[RIDADR ]

UN 3462 6.1/PG 2
[WGK Germany ]

3
[RTECS ]

HA5306000
[F ]

10
[HazardClass ]

6.1(a)
[PackingGroup ]

I
[Toxicity]

cyt-hmn:lym 50 mg/L IJEBA6 16,430,78
Hazard InformationBack Directory
[Uses]

Cytochalasin H is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins, resulting in pronounced morphogenic changes in animals and plants. In vitro, cytochalasin H exhibits antibacterial, antifungal, nematocidal and antitumour activity.
[Safety Profile]

Poison by intravenous and intraperitoneal routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
[storage]

+4°C
Spectrum DetailBack Directory
[Spectrum Detail]

Cytochalasin H(53760-19-3)1HNMR
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