Identification | Back Directory | [Name]
ASP-ARG-VAL-TYR | [CAS]
52580-29-7 | [Synonyms]
DRVY ASP-ARG-VAL-TYR ANGIOTENSIN II (1-4) H-Asp-Arg-Val-Tyr-OH ANGIOTENSIN II (1-4) HUMAN L-Tyrosine, L-α-aspartyl-L-arginyl-L-valyl- | [Molecular Formula]
C24H37N7O8 | [MDL Number]
MFCD00079800 | [MOL File]
52580-29-7.mol | [Molecular Weight]
551.59 |
Hazard Information | Back Directory | [Uses]
Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney[1][2]. | [storage]
Store at -20°C | [References]
[1] De Giusti VC, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. DOI:10.3389/fphys.2013.00411 [2] Moon JY, et al. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-5. DOI:10.5049/EBP.2013.11.2.41 |
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Company Name: |
Ontores Biotech
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Tel: |
0571-88760729 18072970094 |
Website: |
www.ontoresinc.cn |
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