Identification | Back Directory | [Name]
CHONDROITINASE B | [CAS]
52227-83-5 | [Synonyms]
EC 4.2.2.5 CHONDROITINASE B chondroitin B lyase dermatan sulfate Lyase CHONDROITIN SULFATE B LYASE chondroitinase b from flavobacterium heparinum Native Flavobacterium heparinum Chondroitinase B CHONDROITINASE B FROM FLAVOBACTERIUMHEPA RINUM LYOP Chondroitinase B from Flavobacterium heparinum, Recombinant Chondroitinase B from Flavobacterium heparinum lyophilized powder (with BSA as stabilizer) | [MDL Number]
MFCD00166444 |
Hazard Information | Back Directory | [Uses]
Chondroitinase B from Flavobacterium heparinum has been used in a study to assess the structural characterization and antithrombin activity of dermatan sulfate. Chondroitinase B from Flavobacterium heparinum has also been used in a study to investigate the chondroitin lyase action pattern via liquid chromatography–mass spectrometry. | [Biochem/physiol Actions]
Chondroitinase B degrades only chondroitin sulphate B producing oligo- and tetra-saccharides, and an unsaturated 4-sulphated disaccharide. It has an optimum temperature of 20 °C and an optimum pH of 8.0. The enzyme activity is inhibited by 50% using 0.1 M NaCI. Co2+, Fe3+ and Ba2+ also inhibit its activity. |
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