| Identification | Back Directory | [Name]
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride | [CAS]
521284-22-0 | [Synonyms]
Mirabegron INT 3
Mirabegron Impurity M
DarunavirDiamino(2S,3S)Isomer
Mirabegron Impurity 20 Hydrochloride
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]m
(R)-alpha-[[[2-(4-AMinophenyl)ethyl]aMino]Methyl]
(R)-2-(4-aminophenethylamino)-1-
Phenylethanol HCL
(R)-2-[2-(4-Amino-phenyl)-ethylamino]-1-phenyl-ethanol HCl
(R)--[[[2-(4-aminophenyl)ethyl]amino]methyl]-Benzenemethanol
Dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-y/l)phosphonatee'
(R)-2-((4-AMinophenethyl)aMino)-1-phenylethanol hydrochloride
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzen...
(R)-[[[2-(4-aMinophenyl)ethyl]aMino]Methyl]- BenzeneMethanol HCl
(R)-2-((4-aminophenethyl)amino)-1-phenylethanol hydrochloride (1:1)
(R)-2-(4-AMINOPHENETHYL AMINO)-1-PHENYLE THANOL HYDROCHLORIDE / MRG5 HCL
(1R)-2-{[2-(4-Aminophenyl)ethyl]amino}-1-phenylethanol hydrochlor ide (1:1)
(R) -2 - [[2- (4- aminophenyl) ethyl] amino] -1-phenylethanol hydrochloride
alphaR)-alpha-lI12-(4-Aminophenyl)ethylamino]methylbenzenemethanol
hydrochloride
Alphar)-alpha-[[[2-(4-minophenyl)ethyl]amino]methyl] benzenemethanol hydrochloride
(αR) -α-[[[[[(2- (4-aminophenyl) ethyl] amino] methyl] benzyl alcohol hydrochloride
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride
(R) Alpha - [[2- (4-aminophenyl) ethyl] amino] methyl] - benzyl alcohol hydrochloride
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride(For export only)
2H-Pyrrol-2-one,1,5-dihydro-3-hydroxy-4-[3-methyl-4-(phenylmethoxy)benzoyl]-1-[3-(4-morpholinyl)propyl]-5-(10-pyridinyl)- | [EINECS(EC#)]
700-425-8 | [Molecular Formula]
C16H21ClN2O | [MDL Number]
MFCD28124345 | [MOL File]
521284-22-0.mol | [Molecular Weight]
292.81 |
| Chemical Properties | Back Directory | [density ]
1145 at 20℃ | [vapor pressure ]
0.015Pa at 25℃ | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Powder | [Stability:]
Hygroscopic | [LogP]
-1.35 at 20℃ and pH5.79 |
| Hazard Information | Back Directory | [Uses]
(alphaR)-alpha-[[[2-(4-Aminophenyl)ethyl]amino]methyl]benzenemethanol hydrochloride can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes. | [Synthesis]
A mixture of (100 g) (R)-2-[2?ˉ -(4-nitrophenyl)ethyl]amino] -1 -phenylethanol monohydroch bride (prepared according to example Ib), methanol (2000 mL) and Raney Nickel (20 g, wet) was stirred under hydrogen pressure (60 psi) for 6 hrs. The reaction solution was filtered, and the filtrate was concentrated in vacuo. The residue was mixed with isopropanol (300 mL) and reaction mixture was heated to 78??C (?à2). The mixture was added to toluene (900 mL). The reaction mixture was gradually cooled to 28??C (?à2) and stirred at this temperature for 3 hrs. The solid obtained was filtered, washed with toluene and dried under vacuo at 48??C (?à2) to obtain (R)-2-[[2-(4-aminophenyl)ethyl]-amino]- I -phenylethanol monohydrochioride.Yield: 78.1 g (86.1%); Purity by HPLC: 99.14 %. |
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