| Identification | Back Directory | [Name]
4-BROMO-BENZO[B]THIOPHENE | [CAS]
5118-13-8 | [Synonyms]
4-bromo-thiophene
4-Bromothianaphthene
5-cyanobenzothiophene
4-Bromobenzothiophene
4-BROMO-1-BENZOTHIOPHENE
4-BROMO-BENZO[B]THIOPHENE
Brexpiprazole intermdiate
Benzo[b]thiophene,4-broMo-
4-BROMO-BENZO[B]THIOPHENE ISO 9001：2015 REACH
4-Bromo-1-benzothiophene, 4-Bromothianaphthene | [EINECS(EC#)]
814-115-6 | [Molecular Formula]
C8H5BrS | [MDL Number]
MFCD08669544 | [MOL File]
5118-13-8.mol | [Molecular Weight]
213.094 |
| Chemical Properties | Back Directory | [Boiling point ]
144 °C(Press: 20 Torr) | [density ]
1.649±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [form ]
solid | [color ]
White to off-white | [InChI]
InChI=1S/C8H5BrS/c9-7-2-1-3-8-6(7)4-5-10-8/h1-5H | [InChIKey]
QPBSEYFVZDMBFW-UHFFFAOYSA-N | [SMILES]
C12=CC=CC(Br)=C1C=CS2 |
| Questions And Answer | Back Directory | [Synthesis]
The traditional synthesis method is to take 2-bromo-6-fluorobenzaldehyde as a raw material, cyclize the raw material with mercaptoacetic acid in a DMF solvent to obtain 4-chlorobenzo [b] thiophene-2-carboxylic acid, and then decarboxylate the product at a high temperature in a quinoline/copper powder system to obtain the 4-chlorobenzo [b] thiophene. |
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