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ChemicalBook--->CAS DataBase List--->51-77-4

51-77-4

51-77-4 Structure

51-77-4 Structure
IdentificationBack Directory
[Name]

Gefarnate
[CAS]

51-77-4
[Synonyms]

DA 688
Arsanyl
Alsanate
GEFRNATE
Arsanate
Gefarnyl
Terpanil
Gifarnate
Dixnalate
gefarnate
Gefarnate RS
Gefarnate USP/EP/BP
TIANFU CHEM--Gefarnate
Geranyl farnesylacetate
γ-Geraniol farnesylacetate
geranyl 5,9,13-trimethyltetradeca-4,8,12-trienoate
ESTER; ALSANATE; ARSANYL; DA 688; DIXNALATE; GEFANIL
3,7-Dimethylocta-2,6-dien-1-yl 5,9,13-trimethyltetradeca-4,8,12-trienoate
[(2E)-3,7-Dimethylocta-2,6-dienyl] (4E,8E)-5,9,13-trimethyltetradeca-4,8,12-trienoate
(4E,8E)-5,9,13-Trimethyl-4,8,12-tetradecatrienoic acid (E)-3,7-dimethyl-2,6-octadienyl
(4E,8E)-5,9,13-Trimethyl-4,8,12-tetradecatrienoic acid (7-methyl-3-methylene-6-octenyl) ester
4,8,12-Tetradecatrienoic acid, 5,9,13-trimethyl-, (2E)-3,7-dimethyl-2,6-octadienyl ester, (4E,8E)-
4,8,12-Tetradecatrienoicacid, 5,9,13-triMethyl-, (2E)-3,7-diMethyl-2,6-octadien-1-yl ester, (4E,8E)-
[EINECS(EC#)]

200-121-0
[Molecular Formula]

C27H44O2
[MDL Number]

MFCD00129086
[MOL File]

51-77-4.mol
[Molecular Weight]

400.637
Chemical PropertiesBack Directory
[Melting point ]

25°C
[Boiling point ]

bp0.05 165-168°
[density ]

1.0044 (rough estimate)
[refractive index ]

nD20 1.4900
[storage temp. ]

2-8°C
[solubility ]

DMSO:31.25(Max Conc. mg/mL);78.0(Max Conc. mM)
[form ]

Oil
[color ]

Clear Colourless
[Stability:]

Light Sensitive
[EPA Substance Registry System]

4,8,12-Tetradecatrienoic acid, 5,9,13-trimethyl-, (2E)-3,7-dimethyl-2,6-octadienyl ester, (4E,8E)-(51-77-4)
Hazard InformationBack Directory
[Uses]

Gefarnate is a synthetic isoprenoid that is used to treat chronic gastric and duodenic ulcers. Gerfarnate is also used for gastric ulcer prophylaxis.
[Definition]

ChEBI: Gefarnate is an organic molecular entity.
[Biological Activity]

Gefarnate is an anti-ulcer drug th at stimulates gastric mucin secretion. Also gefarnate increase secretion of mucin-like glycoprotein in rabbit conjunctival tissue. It appears to be effective in animal dry-eye models. It is approved in Japanwhere it is used to tre at gastritis and gastric ulcer. Gefarnate is structurally similar to anti-ulcer drug teprenone (geranyl farnesylacetate)which induces expression of HSP70HSPB8and HSPB1.
[storage]

Store at -20°C
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