Identification | Back Directory | [Name]
ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate | [CAS]
503615-07-4 | [Synonyms]
X5909 TECO-012 Apixaban Impurity 81 Apixaban interMediate Intermediates of apixaban Apixaban Impurity 11
ethyl Apixaban Stage-II impurity ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-te... ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-ca ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate 6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester 1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 6-(4-aMinophenyl)-4,5,6,7-tetrahydro-1-(4-Methoxyphenyl)-7-oxo-, ethyl ester Apixaban Impurity 4
ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-
tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate | [EINECS(EC#)]
948-272-8 | [Molecular Formula]
C22H22N4O4 | [MDL Number]
MFCD18251628 | [MOL File]
503615-07-4.mol | [Molecular Weight]
406.434 |
Chemical Properties | Back Directory | [Boiling point ]
651.6±55.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3 (20 ºC 760 Torr) | [storage temp. ]
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | [solubility ]
Chloroform (Slightly), DMF (Slightly) | [form ]
Solid | [pka]
4.66±0.10(Predicted) | [color ]
White to Off-White | [InChI]
InChI=1S/C22H22N4O4/c1-3-30-22(28)19-18-12-13-25(15-6-4-14(23)5-7-15)21(27)20(18)26(24-19)16-8-10-17(29-2)11-9-16/h4-11H,3,12-13,23H2,1-2H3 | [InChIKey]
UVAQGQOGOJLALA-UHFFFAOYSA-N | [SMILES]
C1(=O)N(C2=CC=C(N)C=C2)CCC2C(C(OCC)=O)=NN(C3=CC=C(OC)C=C3)C1=2 |
Hazard Information | Back Directory | [Uses]
Ethyl 6-?(4-?Aminophenyl)?-?1-?(4-methoxyphenyl)?-?7-?oxo-?4,?5,?6,?7-?tetrahydro-?1H-?pyrazolo[3,?4-?c]?pyridine-?3-?carboxylate is an impurity of Apixaban (A726700), A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation. |
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