| Identification | Back Directory | [Name]
L-KAWAIN | [CAS]
500-64-1 | [Synonyms]
KAWAIN
gonosan
L-KAWAIN
Nsc112162
(R)-KAWAIN
(R)-(+)-Kavain
Kawain (200 mg)
L-KAWAIN USP/EP/BP
5,6-Dihydro-4-methoxy-6-styryl-2-pyron
5,6-Dihydro-4-methoxy-6-styryl-2H-pyran-2-one
6-dihydro-4-methoxy-6-styryl-(r)-2h-pyran-2-on
(r)-5,6-dihydro-4-methoxy-6-styryl-2h-pyran-2-one
[R-(E)]-5,6-dihydro-4-methoxy-6-styryl-2H-pyran-2-one
2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (+)-
2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-styryl-, (R)-
4-methoxy-6-(beta-phenylvinyl)-5,6-dihydro-alpha-pyrone
5-hydroxy-3-methoxy-7-phenyl-2,6-heptadienoicacidgamma-lactone
(R)-5,6-Dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one
(6R)-5,6-Dihydro-4-methoxy-6-[(E)-2-phenylethenyl]-2H-pyran-2-one
2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-(2-phenylethenyl)-, [R-(E)]-
2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[(1E)-2-phenylethenyl]-, (6R)- | [EINECS(EC#)]
207-907-2 | [Molecular Formula]
C14H14O3 | [MDL Number]
MFCD00467093 | [MOL File]
500-64-1.mol | [Molecular Weight]
230.26 |
| Chemical Properties | Back Directory | [Melting point ]
142-148℃ | [alpha ]
D20 +105° (abs alc) | [Boiling point ]
bp0.1 195-197° | [density ]
1.1914 (rough estimate) | [refractive index ]
1.5557 (estimate) | [storage temp. ]
Amber Vial, -20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), Ethanol (Slightly, Sonicated), Methanol (Slightly) | [form ]
Solid | [color ]
White to Light Yellow | [Stability:]
Light Sensitive | [LogP]
0.784 (est) |
| Hazard Information | Back Directory | [Originator]
Largon,Klinge | [Uses]
Kawain is a plant extract that shows antioxidant activity through cyclooxygenase enzyme inhibition. May also be active in tumor suppression and apoptotic induction. | [Definition]
ChEBI:Kawain is a member of 2-pyranones and an aromatic ether. | [Manufacturing Process]
To 1170 g ethyl acetoacetate at 100-110°C was added a little at time 1605 g
bromosuccinimide. After cooling to the mixture was added 300 ml of carbon
tetrachloride. From the mixture was isolated ethyl ester of bromoacetoacetic
acid which was distilled at 105-125°C/18 mm; yield 67%.
By condensation of the mixture 1400 g ethyl ester of bromoacetoacetic acid,
700 g bromosuccineimide, 500 ml benzene and 350 mg zinc was prepared
(R)-5,6-dihydro-4-methoxy-6-styryl-2H-pyran-2-one; melting point 157°C,
yield 60-70%. | [Therapeutic Function]
Anesthetic; Tranquilizer | [storage]
Store at -20°C |
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