| Hazard Information | Back Directory | [Description]
Prostaglandin E2 (PGE2; ) activates four E prostanoid (EP) receptors, EP1-4. EP4 is a G protein-coupled receptor that, by elevating the second messenger cAMP, plays important roles in bone formation and resorption, cancer, and atherosclerosis. CAY10684 is a lactam that acts as a potent EP4 agonist, triggering cAMP signaling with an EC50 value of 0.8 nM. It displays more than 1,000-fold selectivity for EP4 over other EP receptors. | [Uses]
(2R)-2-[(1E)-3-(4''-Chloro-2''-methyl[1,1''-biphenyl]-3-yl)-3-hydroxy-1-propen-1-yl]-5-oxo-1-pyrrolidineheptanoic Acid is an EP4 receptor agonist. |
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| Company Name: |
BOC Sciences
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16314854226 |
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www.bocsci.com |
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