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ChemicalBook--->CAS DataBase List--->474922-84-4

474922-84-4

474922-84-4 Structure

474922-84-4 Structure
IdentificationBack Directory
[Name]

1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal
[CAS]

474922-84-4
[Synonyms]

16:0 PEG3000 PE
16:0 PEG5000 PE
16:0 PEG2000 PE
16:0 PEG1000 PE
16:0 PEG PE, MW 350
DipalmitoylphosphatidylethanolamineN-[methoxy(polyethylene glycol)-2000]
1,2-dipalMitoyl-sn-glycero-3-phosphoethanolaMine-N-[Methoxy(polyethylene glycol)-1000] (aMMoniuM sal
alpha-[(9R)-6-Hydroxy-6-oxido-1,12-dioxo-9-[(1-oxohexadecyl)oxy]-5,7,11-trioxa-2-aza-6-phosphaheptacos-1-yl]-omega-methoxypoly(oxy-1,2-ethanediyl) ammonium salt
[Molecular Formula]

(C2H4O)n.C39H76NO10P.NH3
[MDL Number]

MFCD02262261
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Description]

16:0 PEG PE, MW 1,100 is a PEG-modified phospholipid conjugate used in liposome formation of sterically stabilized liposomes with low reticuloendothelial system uptake and increased circulation duration to target cells.
[Uses]

16:0 PEG2000 PE, or 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] has been used in liposome preparation. It has also been used in preparation of tripeptide arginine-glycine-aspartic acid magnetoliposomes (RGD-MLPs) and poly(ethylene glycol) (PEG)- MLPs.
[Uses]

16:0 PEG3000 PE is suitable for the preparation of liposome and advanced drug delivery nano liposomal system.
[Uses]

16:0 PEG5000 PE or 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 has been used in preparation of lipid bilayer. It has also been used in liposome preparation.
[General Description]

16:0 PEG5000 PE, also known as 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-5000 (DPPE-PEG 5000), is a mPEG phospholipid conjugate. Poly(ethylene glycol) (PEG)-based liposomal formulations are widely used in preparation of biocompatible self-assembled drug-delivery systems. These systems have an ability to escape the recognition and uptake by cells in the immune system at the same time it extends the residence time of the liposomes and allows continuous drug release into the targeted cells.
[Biochem/physiol Actions]

Polyethylene glycol (PEG) conjugated phospholipids are useful in liposome formulation for maintaining their stereochemistry. They also serve as drug carriers. PEGylated lipids aid in the formation of mixed micelles at high concentration.
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