| Identification | Back Directory | [Name]
GAMABUFOTALIN | [CAS]
465-11-2 | [Synonyms]
Gamabufagin
Gamabufogenin
GAMABUFOTALIN
GAMABUFOTALIN USP/EP/BP
GAMABUFOTALIN 465-11-2
Gamabufotalin (Gamabufagin)
3,11,14-Trihydroxybufa-20,22-dienolide
3β,11α,14-Trihydroxy-5β-bufa-20,22-dienolide
Bufa-20,22-dienolide,3,11,14-trihydroxy-, (3b,5b,11a)-
Bufa-20,22-dienolide, 3,11,14-trihydroxy-, (3β,5β,11α)-
22-dienolide,3-beta,11-alpha,14-trihydroxy-5-beta-bufa-2
5beta-Bufa-20,22-dienolide, 3beta,11alpha,14-trihydroxy-
3-beta,11-alpha,14-Trihydroxy-5-beta-bufa-20,22-dienolide
22-dienolide,3,11,14-trihydroxy-,(3-beta,5-beta,11-alpha)-bufa-2
Bufa-20,22-dienolide, 3,11,14-trihydroxy-, (3beta,5beta,11alpha)-
5-[(3S,5R,8R,9S,10S,11R,13R,14S,17R)-3,11,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]pyran-2-one
5-[(3S,5R,8R,9S,10S,11R,13R,14S,17R)-3,11,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-pyranone | [Molecular Formula]
C24H34O5 | [MDL Number]
MFCD01740822 | [MOL File]
465-11-2.mol | [Molecular Weight]
402.52 |
| Chemical Properties | Back Directory | [Melting point ]
254° | [alpha ]
D18 +1.26° (c = 0.793 in methanol) | [Boiling point ]
595.8±50.0 °C(Predicted) | [density ]
1.289±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
14.52±0.70(Predicted) | [color ]
White to off-white | [CAS DataBase Reference]
465-11-2 |
| Hazard Information | Back Directory | [Description]
Gamabufotalin belongs to the bufastenolide compound contained in traditional Chinese medicine toadstool. Previous studies have shown that CS-6 has a good effect in inhibiting tumor cell growth and inflammatory response. | [Chemical Properties]
White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from toad secretions. | [Uses]
Gamabufotalin has a strong heart and anti-tumor effect. | [Definition]
ChEBI:Gamabufogenin is a steroid lactone. It is functionally related to a bufanolide. | [Biological Activity]
Gamabufotalin (Gamabufagin), the main bufastenene in Bufonis bufa, is widely used in cancer research due to its stability and low toxicity. |
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