Identification | Back Directory | [Name]
arenobufagin | [CAS]
464-74-4 | [Synonyms]
arenobufagin Arenobufogenin Arenobufagin, BR arenobufagin USP/EP/BP 3β,11α,14-Trihydroxy-12-oxo-5β-bufa-20,22-dienolide Bufa-20,22-dienolide,3,11,14-trihydroxy-12-oxo-, (3b,5b,11a)- Bufa-20,22-dienolide, 3,11,14-trihydroxy-12-oxo-, (3β,5β,11α)- (3beta,5beta,8xi,9xi,11alpha)-3,11,14-trihydroxy-12-oxobufa-... (3beta,5beta,11alpha)-3,11,14-Trihydroxy-12-oxobufa-20,22-dienolide (3beta,5beta,8xi,9xi,11alpha)-3,11,14-trihydroxy-12-oxobufa-20,22-dienolide | [Molecular Formula]
C24H32O6 | [MDL Number]
MFCD01740820 | [MOL File]
464-74-4.mol | [Molecular Weight]
416.511 |
Chemical Properties | Back Directory | [Melting point ]
222-228℃ | [Boiling point ]
637.2±55.0 °C(Predicted) | [density ]
1.349 | [storage temp. ]
2-8°C | [solubility ]
DMF: 10 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:8): 0.11 mg/ml | [form ]
A crystalline solid | [pka]
12.39±0.70(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
Arenobufagin is a cardiotoxic bufanolide steroid secreted by the Argentine toad Bufo arenarum. It has effects similar to digitalis, blocking the Na+/K+ pump in heart tissue. |
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