| Identification | Back Directory | [Name]
BMS CCR22 22 | [CAS]
445479-97-0 | [Synonyms]
BMS CCR2 22
BMS CCR22 22
CCR2 inhibitor BMS 22
BMS CCR2 22,BMS CCR-2 22
2-[(Isopropylaminocarbonyl)amino]-N-[2-[[cis-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide
rel-2-[[[(1-Methylethyl)amino]carbonyl]amino]-N-[2-[[(1R,2S)-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)benzamide
Benzamide, 2-[[[(1-methylethyl)amino]carbonyl]amino]-N-[2-[[(1R,2S)-2-[[4-(methylthio)benzoyl]amino]cyclohexyl]amino]-2-oxoethyl]-5-(trifluoromethyl)-, rel- | [Molecular Formula]
C28H34F3N5O4S | [MDL Number]
MFCD11519960 | [MOL File]
445479-97-0.mol | [Molecular Weight]
593.66 |
| Chemical Properties | Back Directory | [Boiling point ]
764.9±60.0 °C(Predicted) | [density ]
1.33±0.1 g/cm3(Predicted) | [storage temp. ]
Store at +4°C | [solubility ]
Soluble to 100 mM in DMSO and to 10 mM in ethanol | [form ]
Powder | [pka]
12.59±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
BMS CCR2 22 (cas# 445479-97-0) is a novel competitive CCR2 antagonist. | [Biological Activity]
High affinity CCR2 chemokine receptor antagonist (IC 50 = 5.1 nM). Displays potent functional antagonism, IC 50 values are 1 and 18 nM for antagonism of calcium flux and chemotaxis respectively. Selective over CCR3. | [storage]
Store at -20°C |
|
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310 |
| Website: |
http://www.weikeqi-biotech.com/ |
|