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ChemicalBook--->CAS DataBase List--->4452-06-6

4452-06-6

4452-06-6 Structure

4452-06-6 Structure
IdentificationBack Directory
[Name]

ZM 449829
[CAS]

4452-06-6
[Synonyms]

ZM 449829
JAK3 INHIBITOR V
2'-Acrylonaphthone
naphthyl vinyl ketone
2-NAPHTHYLVINYL KETONE
1-Naphthalen-2-yl-propenone
1-(2-Naphthyl)-2-propen-1-one
1-(2-NAPHTHALENYL)-2-PROPEN-1-ONE
1-(Naphthalen-2-yl)prop-2-en-1-one
2-Propen-1-one, 1-(2-naphthalenyl)-
JAK3 Inhibitor V - CAS 932258 - Calbiochem
[Molecular Formula]

C13H10O
[MDL Number]

MFCD04974535
[MOL File]

4452-06-6.mol
[Molecular Weight]

182.22
Chemical PropertiesBack Directory
[Boiling point ]

319.3±15.0 °C(Predicted)
[density ]

1.093±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Sealed in dry,Store in freezer, under -20°C
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

White waxy solid
Safety DataBack Directory
[Symbol(GHS) ]


GHS06,GHS08
[Signal word ]

Danger
[Hazard statements ]

H301-H311-H331-H341
[Precautionary statements ]

P201-P202-P261-P264-P270-P271-P280-P302+P352-P304+P340-P308+P313-P310-P330-P361-P403+P233-P405-P501
Hazard InformationBack Directory
[Uses]

ZM 449829, is a potent, selective inhibitor of JAK3 (Janus tyrosine kinase 3) which binds competitively to the JAK3 ATP site. Also inhibits STAT-5 phosphorylation and T-cell proliferation.
[Definition]

ChEBI: 1-(2-naphthalenyl)-2-propen-1-one is a member of naphthalenes.
[storage]

Desiccate at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

ZM 449829(4452-06-6)1HNMR
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