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ChemicalBook--->CAS DataBase List--->443776-49-6

443776-49-6

443776-49-6 Structure

443776-49-6 Structure
IdentificationBack Directory
[Name]

BC 11 hydrobroMide
[CAS]

443776-49-6
[Synonyms]

BC 11 hydrobroMide
Carbamimidothioic acid (4-boronophenyl)methyl ester hydrobromide
[Molecular Formula]

C8H12BBrN2O2S
[MDL Number]

MFCD20926359
[MOL File]

443776-49-6.mol
[Molecular Weight]

290.97
Chemical PropertiesBack Directory
[Melting point ]

177 - 182°C
[storage temp. ]

Hygroscopic, Refrigerator, Under inert atmosphere
[solubility ]

Aqueous Base (Slightly), DMSO (Slightly), Water (Slightly)
[form ]

Solid
[color ]

White to Off-White
[Water Solubility ]

H2O: 2mg/mL, clear (warmed)
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Uses]

BC 11 Hydrobromide, is a selective urokinase (uPA) inhibitor. It inhibits clot lysis without haveing any effect on clot formation. It has also shown to be able to decrease viability of MDA-MB231 breast cancer cells in vitro.
[Biological Activity]

BC-11 is a potent and selective inhibitor of urokinase (urokinase-plasminogen activatoruPA). BC-11 inhibits clot lysis with no effect on clot formation. BC-11 exhibits anti-fibrotic activity and improves wound healing and scar quality after topical administration in mice.
[storage]

Store at -20°C
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