Identification | Back Directory | [Name]
TABERSONINE | [CAS]
4429-63-4 | [Synonyms]
C09244 tabersonin abersonine TABERSONINE TABERSONINE(SH) ,12-beta,19-alpha)- Tabersonine 4429-63-4 Hydrochloric acid it Boning Tabersonine, 98%, from Voacanga africana Staph. Tabersonine Hydrochloride,from Vocanga Africana TABERSONINE HYDROCHLORIDE FROM VOCANGA AFRICANA 98% Methyl (5α,12β,19α)-2,3,6,7-tetradehydroaspidospermidine-3-carboxylate aspidospermidine-3-carboxylicacid,2,3,6,7-tetrahydro-,methylester,(5-alpha (5α,12β,19α)-2,3,6,7-Tetrahydro-aspidospermidine-3-carboxylic acid methyl ester (5α,12R,19α)-2,3,6,7-TetradehydroaspidosperMidine-3-carboxylic Acid Methyl Ester AspidosperMidine-3-carboxylicacid, 2,3,6,7-tetradehydro-, Methyl ester, (5a,12R,19a)- Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-, methyl ester, (5α,12R,19α)- 3a-Ethyl-3a,4,6,11,12,13a-hexahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylic Acid Methyl Ester Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-, methyl ester, (5alpha,12beta,19alpha)- | [EINECS(EC#)]
224-615-0 | [Molecular Formula]
C21H24N2O2 | [MDL Number]
MFCD01632757 | [MOL File]
4429-63-4.mol | [Molecular Weight]
336.43 |
Chemical Properties | Back Directory | [Occurrence]
The seeds of Amsonia elliptica contain this N-oxide at tabersonine. | [Melting point ]
196 °C | [Boiling point ]
488.7±45.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [solubility ]
Chloroform (Slightly), Ethanol (Slightly, Sonicated), Ethyl Acetate (Slightly) | [form ]
Solid | [pka]
7?+-.0.60(Predicted) | [color ]
Light Yellow to Dark Yellow | [Stability:]
Light Sensitive |
Hazard Information | Back Directory | [Chemical Properties]
Dark Yellow Low Melting Solid | [Uses]
(-)-Tabersonine is one of the terpenoid indole alkaloids (TIAs) from Catharanthus roseus. (-)-Tabersonine shows hypotensive activity, anti-tumor activity, hypoglycemic, diuretic activity. | [Definition]
ChEBI: A monoterpenoid indole alkaloid with cytotoxic activity. | [Description]
This alkaloid, found in Amsonia tabernaemontana, is difficult to obtain crystalline
but the hydrochloride is readily crystallizable and has m.p. 195-6°C; [α]D -
310° (c 0.134, MeOH). | [References]
lanot, Paourrat, LeMen., Bull. Soc. Chim. Fr., 707 (1954)
Plat et al., Tetrahedron Lett., 271 (1962) |
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