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ChemicalBook--->CAS DataBase List--->42509-80-8

42509-80-8

42509-80-8 Structure

42509-80-8 Structure
IdentificationBack Directory
[Name]

ISAZOPHOS
[CAS]

42509-80-8
[Synonyms]

MIRAL
brace
a-12223
ISAZOFOS
MIRAL(R)
miral10g
Brace 10G
ISAZOPHOS
cga-12223
ciba12223
ai3-29128
Protriazophos
ISAZOFOS STANDARD
Ciba-Geigy A 12223
Isazofos,ISAZOPHOS
Isazophos Standard
ISAZOPHOS, 1GM, NEAT
Triumph (insecticide)
ISAZOPHOS PESTANAL
isazophos (bsi,iso,ansi)
Isazofos solution,100ppm
O-DIETHYL-PHOSPHORTHIOATE
Isazofos Solution, 1000ppm
Isazophos 1g [42509-80-8]
Isazophos Solution, 100ppm
Isazofos Solution in Acetone
Isazophos @100 μg/mL in MeOH
Isazophos@1000 μg/mL in Methanol
O-5-CHLORO-1-ISOPROPYL-1H-1,2,4-TRIAZOLYL-O
o-5-chloro-1-isopropyl-1h-1,2,4-triazol-3-ylo,o-diethylphosphorothioate
O-(5-chloro-1-isopropyl-1,2,4-triazol-3-yl) O,O-diethyl phosphorothioate
O,O-DIETHYL-O-[1-ISOPROPYL-5-CHLORO-1,2,4-TRIAZOLYL-[3]]-PHOSPHOROTHIOATE
o-(5-chloro-1-isopropyl-1h-1,2,4-triazol-3-yl)o,o-diethylphosphorothioate
o-(5-chloro-1-(1-methylethyl)-1h-1,2,4-triazol-3-yl)o,o-phosphorothioicaci
o-(5-chloro-1-(1-methylethyl)-1h-1,2,4-triazol-3-yl)o,o-diethylphosphorothi
O-(5-chloro-1-isopropyl-1H-1,2,4-triazol-3-yl)-O,O-diethyl phosphorothhioate
O,O-diethyl-O-(5-chloro-1-methylethyl-1H-1,2,4-triazol-3-yl) phosphorthioate
O-(5-chloro-1-(1-methylethyl)-1H-1,2,4-triazol-3-yl)-O,O-diethyl phosphorothioate
O-(5-chloro-1-isopropyl-1,2,4-triazol-3-yl) O,O-diethyl phosphorothioate isazofos
Thiophosphoric acid O,O-diethyl O-(5-chloro-1-isopropyl-1H-1,2,4-triazol-3-yl) ester
Phosphorothioic acid, O-5-chloro-1-(1-methylethyl)-1H-1,2,4-triazol-3-yl O,O-diethyl ester
[EINECS(EC#)]

255-863-8
[Molecular Formula]

C9H17ClN3O3PS
[MDL Number]

MFCD00078699
[MOL File]

42509-80-8.mol
[Molecular Weight]

313.74
Chemical PropertiesBack Directory
[Melting point ]

<25℃
[Boiling point ]

bp0.001 100°; bp760 170°
[density ]

1.22 g/cm3 (20℃)
[vapor pressure ]

7.45 x 10-3 Pa (20 °C)
[refractive index ]

nD20 1.4867
[storage temp. ]

0-6°C
[form ]

liquid
[pka]

-1.47±0.10(Predicted)
[Water Solubility ]

168 mg l-1 (20 °C)
[BRN ]

8145294
[EPA Substance Registry System]

Isazofos (42509-80-8)
Safety DataBack Directory
[Hazard Codes ]

T+,N
[Risk Statements ]

24/25-26-43-48/20-50/53
[Safety Statements ]

28-36/37-38-45-59-61
[RIDADR ]

3018
[WGK Germany ]

3
[RTECS ]

TE7760000
[HazardClass ]

6.1(a)
[PackingGroup ]

II
[HS Code ]

29339900
[Hazardous Substances Data]

42509-80-8(Hazardous Substances Data)
[Toxicity]

LD50 in rats (mg/kg): 60 orally; 250-700 dermally (Dawes)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Potassium carbonate-->Urea-->PHOSGENE-->2-Bromopropane-->METHYLISOCYANATE 1 X 500MG NEAT-->Isoxazole-->cyanic acid
Hazard InformationBack Directory
[Description]

Isazofos is a yellow liquid. Solubility in water is 168 mg/L (20 ?C). It is miscible with common organic solvents. Log Kow = 2.99. It is hydrolyzed in aqueous media: DT50 values (20 ?C) at pH 5, 7, and 9 are 85, 48, and 19 d, respectively.
[Uses]

Isazofos is used as a nematicide and soil insecticide in bananas, citrus, cotton, beet, maize, rice, vegetables, sugar cane and turf.
[Uses]

Nematocide; turf insecticide.
[Definition]

ChEBI: Isazofos is an organic thiophosphate.
[Metabolic pathway]

Isazofos is metabolised in soil to its hydrolysis product 5-chloro-1- isopropyl-3-triazolol. The oxon metabolite has apparently not been identified.
[Metabolism]

In mammals, administered isazofos is rapidly metabolized and excreted, primarily in the urine, without accumulation in the body. The degradation route of isazofos in soil is primarily the hydrolysis mediated by microorganisms to give 5-chloro-1-isopropyl-3-triazole. The half-life in soils is about 10 d.
[Degradation]

Isazofos is hydrolysed more rapidly in alkaline rather than acid solution. The DT50 values at pH 5, 7 and 9 were 85, 48 and 19 days, respectively (PM).
[Toxicity evaluation]

Acute oral LD50 for rats is 40–60 mg/kg. Inhalation LC50 (4 h) for rats is about 0.24 mg/L air. NOEL (90 d) for rats is 2 mg/kg diet (0.1 mg/kg/d).
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