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ChemicalBook--->CAS DataBase List--->4152-92-5

4152-92-5

4152-92-5 Structure

4152-92-5 Structure
IdentificationBack Directory
[Name]

[2-(aminomethyl)phenyl]methanol
[CAS]

4152-92-5
[Synonyms]

RARECHEM GT HW 0287
UKRORGSYN-BB BBV-182531
o-(Hydroxymethyl)benzylamine
[2-(aminomethyl)phenyl]methanol
[Molecular Formula]

C8H11NO
[MDL Number]

MFCD09035091
[MOL File]

4152-92-5.mol
[Molecular Weight]

137.18
Chemical PropertiesBack Directory
[Boiling point ]

271℃
[density ]

1.113
[Fp ]

118℃
[storage temp. ]

Keep in dark place,Inert atmosphere,2-8°C
[pka]

14.28±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

[2-(aminomethyl)phenyl]methanol can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
[Synthesis]

(4-Aminomethyl-phenyl)-methanol hydrochloride salt 4-Hydroxymethyl-benzonitrile (2.0 g, 15 mol) was reduced using Raney nickel (0. 5g) and hydrogen (50 psi) in MeOH: NH3 (100ml) for 20 hours. The reaction mixture was filtered through a pad of celite. The filtrate was concentrated under reduced pressure to afford (4-aminomethyl-phenyl)-methanol hydrochloride salt (2.01 g, 98percent) as a white solid of sufficient purity for use without further purification: MS (APCI+) : m/z 138.3 (M+H).
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