| Identification | Back Directory | [Name]
Fluprostenol | [CAS]
40666-16-8 | [Synonyms]
FLUPROSTENOL
WWSWYXNVCBLWNZ-QIZQQNKQSA-N
FLUPROSTENOL, ETHANOL SOLUTION
Travoprost Impurity 31((±)-Fluprostenol)
(±)-16-(3-trifluoromethylphenoxy)tetranorprostaglandin f2α
(+/-)-16-(3-TRIFLUOROMETHYLPHENOXY)TETRANORPROSTAGLANDIN F2ALPHA
(+/-)16-(M-TRIFLUOROMETHYLPHENOXY)-TETRANOR-PROSTAGLANDIN F2ALPHA
(+/-)-9ALPHA,11ALPHA,15R-TRIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19, 20-TETRANORPROSTA 5Z,13E-DIEN-1-OIC ACID
(5Z)-rel-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic acid
5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, (5Z)-rel- | [EINECS(EC#)]
255-029-3 | [Molecular Formula]
C23H29F3O6 | [MDL Number]
MFCD03427566 | [MOL File]
40666-16-8.mol | [Molecular Weight]
458.47 |
| Hazard Information | Back Directory | [Uses]
Fluprostenol is a prostaglandin F (FP) receptor agonist. | [Definition]
ChEBI: Fluprostenol is an organofluorine compound that is racemic prostaglandin F2alpha in which the pentyl group is replaced by a 3-(trifluoromethyl)phenoxymethyl group. A synthetic analogue of prostaglandin F2alpha, ophthalmic solutions of its isopropyl ester prodrug, travoprost, are used as a topical medication for controlling the progression of open-angle glaucoma and ocular hypertension, by reducing intraocular pressure. The isopropyl ester group of travoprost is hydrolysed to the biologically active free acid by esterases in the cornea. It has a role as an antiglaucoma drug, an antihypertensive agent, a prostaglandin receptor agonist, a female contraceptive drug and an abortifacient. It is a prostaglandins Falpha, a hydroxy monocarboxylic acid and a member of (trifluoromethyl)benzenes. |
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