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ChemicalBook--->CAS DataBase List--->3947-65-7

3947-65-7

3947-65-7 Structure

3947-65-7 Structure
IdentificationBack Directory
[Name]

(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL
[CAS]

3947-65-7
[Synonyms]

U-5214
neamin
C01441
NEAMINE
neomycina
Negamicin
dekamycinv
nebramycinx
Neamine CRS
Framycetin EP Impurity A
Neomycin sulfate impurity A
Neomycin A sulfate (Neamine)
Neomycin Sulfate EP Impurity A
Neomycin Sulfate EP Impurity A (Neamine)
Framycetin Impurity 1 (Framycetin EP Impurity A)
Tobramycin Impurity 3 (Tobramycin EP Impurity C) (Neamine)
Neomycin Sulfate Impurity 1(Neomycin Sulfate EP Impurity A)
2-Deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-D-streptamine
D-Streptamine, 2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-
2-deoxy-4-o-(2,6-diamino-2,6-dideoxy-alpha-d-glucopyranosyl)-d-streptamin
5-amino-2-(aminomethyl)-6-(4,6-diamino-2,3-dihydroxycyclohexyl)oxyoxane-3,4-diol
5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL
2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-D-streptamine (neamine or neomycin A-LP)
(1R,3S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL
(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL
(2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-(((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl)oxy)tetrahydro-2H-pyran-3,4-diol
[Molecular Formula]

C12H26N4O6
[MDL Number]

MFCD03001759
[MOL File]

3947-65-7.mol
[Molecular Weight]

322.36
Chemical PropertiesBack Directory
[Melting point ]

225.5°C (rough estimate)
[alpha ]

D25+112.8° (c = 1)
[Boiling point ]

460.98°C (rough estimate)
[density ]

1.1885 (rough estimate)
[refractive index ]

1.6120 (estimate)
[storage temp. ]

Hygroscopic, Refrigerator, Under inert atmosphere
[solubility ]

Aqueous Acid (Slightly), Methanol (Slightly, Heated), Water (Slightly)
[form ]

neat
[pka]

13.24±0.70(Predicted)
[color ]

White to Pale Yellow
[Stability:]

Hygroscopic
Hazard InformationBack Directory
[Uses]

Neamine is normally found as a core structure of aminoglycoside antibiotics. It is used in the synthesis of disaccharide neamine derivatives as antibacterial agents.
[Definition]

ChEBI: 2-Deoxy-D-streptamine glycosylated at the 4-oxygen with a 6-amino-alpha-D-glucosaminyl group.
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