Identification | Back Directory | [Name]
(1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL | [CAS]
3947-65-7 | [Synonyms]
U-5214 neamin C01441 NEAMINE neomycina Negamicin dekamycinv nebramycinx Neamine CRS Framycetin EP Impurity A Neomycin sulfate impurity A Neomycin A sulfate (Neamine) Neomycin Sulfate EP Impurity A Neomycin Sulfate EP Impurity A (Neamine) Framycetin Impurity 1 (Framycetin EP Impurity A) Tobramycin Impurity 3 (Tobramycin EP Impurity C) (Neamine) Neomycin Sulfate Impurity 1(Neomycin Sulfate EP Impurity A) 2-Deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-D-streptamine D-Streptamine, 2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)- 2-deoxy-4-o-(2,6-diamino-2,6-dideoxy-alpha-d-glucopyranosyl)-d-streptamin 5-amino-2-(aminomethyl)-6-(4,6-diamino-2,3-dihydroxycyclohexyl)oxyoxane-3,4-diol 5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL 2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-D-streptamine (neamine or neomycin A-LP) (1R,3S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL (1'R,3'S,3S,5R,6R)-5-AMINO-2-AMINOMETHYL-6-(4,6-DIAMINO-2,3-DIHYDROXY-CYCLOHEXYLOXY)-TETRAHYDRO-PYRAN-3,4-DIOL (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-(((1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl)oxy)tetrahydro-2H-pyran-3,4-diol | [Molecular Formula]
C12H26N4O6 | [MDL Number]
MFCD03001759 | [MOL File]
3947-65-7.mol | [Molecular Weight]
322.36 |
Chemical Properties | Back Directory | [Melting point ]
225.5°C (rough estimate) | [alpha ]
D25+112.8° (c = 1) | [Boiling point ]
460.98°C (rough estimate) | [density ]
1.1885 (rough estimate) | [refractive index ]
1.6120 (estimate) | [storage temp. ]
Hygroscopic, Refrigerator, Under inert atmosphere | [solubility ]
Aqueous Acid (Slightly), Methanol (Slightly, Heated), Water (Slightly) | [form ]
neat | [pka]
13.24±0.70(Predicted) | [color ]
White to Pale Yellow | [Stability:]
Hygroscopic |
Hazard Information | Back Directory | [Uses]
Neamine is normally found as a core structure of aminoglycoside antibiotics. It is used in the synthesis of disaccharide neamine derivatives as antibacterial agents. | [Definition]
ChEBI: 2-Deoxy-D-streptamine glycosylated at the 4-oxygen with a 6-amino-alpha-D-glucosaminyl group. |
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