Identification | Back Directory | [Name]
2,2'-Cyclouridine | [CAS]
3736-77-4 | [Synonyms]
Anhydro-U 2,2'-Anhydro-U 02,2-Cycloridine 2,2'-Cyclouridine O2,2'-CYCLOURIDINE 2,2'-ANHYDROURIDINE 2,2'-O-Cyclouridine β-D-O2,2′-Cyclouridine 2,2'-Anhydro-D-uridine O(sup 2),2'-cyclouridine BETA-D-O(2),2'-CYCLOURIDINE 2,2'-Anhydro-1(beta-D-Arabinof 3736-77-4 2,2'-Anhydrouridine 7410 2,2'-Anhydro-1(-D-arabinofuranosyl)uracil β-D-O2,2μ-Cyclouridine, O2,2μ-Cyclouridine 2,2''-ANHYDRO-1(SS-D-ARABINOFURANOSYL)URACIL 2, 2''-ANHYDROURIDINE (2, 2''-O-CYCLOURIDINE) 2, 2'-ANHYDRO-1-(B-D-ARABINOFURANOSYL) URACIL 2,2'-ANHYDRO-1(BETA-D-ARABINOFURANOSYL)URACIL 2,2'-O-Anhydro-(1-β-D-arabinofuranosyl)uracil 2,2'-O-Anhydro-(1-beta-D-arabinofuranosyl)uracil 2,2'-ANHYDRO-(1-B-D-ARABINOFURANOSYL)URA CIL FREE B 2,2'-O-Anhydro-(1-beta-D-arabinofuranosyl)uracil
O2,2′-Cyclouridine 2,2'-Cyclouridine
2,2'-Anhydro-1-(beta-D-arabinofuranosyl) uracil (2R)-2,3,3aβ,9aβ-Tetrahydro-3β-hydroxy-2α-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one (2R,3aβ,9aβ)-2,3,3a,9a-Tetrahydro-3β-hydroxy-2α-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one (2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-2-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one [2R-(2alpha,3beta,3abeta,9abeta)]-2,3,3a,9a-tetrahydro-3-hydroxy-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one | [EINECS(EC#)]
223-107-6 | [Molecular Formula]
C9H10N2O5 | [MDL Number]
MFCD00004945 | [MOL File]
3736-77-4.mol | [Molecular Weight]
226.19 |
Chemical Properties | Back Directory | [Melting point ]
248-251 °C(lit.)
| [alpha ]
-21°(19℃, c=4, H2O) | [Boiling point ]
456.3±55.0 °C(Predicted) | [density ]
2.01±0.1 g/cm3(Predicted) | [refractive index ]
-20 ° (C=4, H2O) | [storage temp. ]
Store at RT. | [solubility ]
DMSO:2.0(Max Conc. mg/mL);8.84(Max Conc. mM) PBS (pH:7.2):1.0(Max Conc. mg/mL);4.42(Max Conc. mM) | [form ]
powder to crystal | [pka]
12.55±0.40(Predicted) | [color ]
White to Almost white | [optical activity]
[α]19/D 21°, c = 4 in H2O | [InChI]
InChI=1S/C9H10N2O5/c12-3-4-6(14)7-8(15-4)11-2-1-5(13)10-9(11)16-7/h1-2,4,6-8,12,14H,3H2/t4-,6-,7+,8-/m1/s1 | [InChIKey]
UUGITDASWNOAGG-CCXZUQQUSA-N | [SMILES]
C12O[C@@]3([H])[C@H](O)[C@@H](CO)O[C@@]3([H])N1C=CC(=O)N=2 | [CAS DataBase Reference]
3736-77-4 |
Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
Research tool for antiviral and anticancer studies.1 | [Description]
2,2'-Anhydro-1(B-D-arabinofuranosyl)uracil is a research tool for anticancer and antiviral studies. This works by inhibiting uridine phosphorylase, a key enzyme targeted by some antitumor drugs. | [storage]
Store at -20°C |
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