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ChemicalBook--->CAS DataBase List--->36622-28-3

36622-28-3

36622-28-3 Structure

36622-28-3 Structure
IdentificationBack Directory
[Name]

S(-)-VERAPAMIL
[CAS]

36622-28-3
[Synonyms]

LU 33926
S(-)-VERAPAMIL
S-Verapamil HCL
S(-)-VERAPAMIL HYDROCHLORIDE
S(-)-VERAPAMIL HYDROCHLORIDE HYDRATE
S(-)-Verapamil hydrate hydrochloride
[7-cyano-1,7-bis(3,4-dimethoxyphenyl)nonan-3-yl]ammonium chloride
(-)-[3-cyano-3-(3,4-dimethoxyphenyl)hex-6-yl][2-(3,4-dimethoxyphenyl)ethyl]methylammonium chloride
(2S)-2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile:hydrochloride
Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, monohydrochloride, (S)-
Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl) ethyl]methylamino]propyl]-3,4-dimethoxy -α-(1-methylethyl)-, monohydrochloride, (αS)-
Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, monohydrochloride, (aS)- (9CI)
[EINECS(EC#)]

253-132-8
[Molecular Formula]

C27H38N2O4
[MDL Number]

MFCD00869809
[MOL File]

36622-28-3.mol
[Molecular Weight]

454.6
Chemical PropertiesBack Directory
[solubility ]

H2O: >30 mg/mL
[form ]

solid
[color ]

white
[optical activity]

[α]22/D 6.1°, c = 0.1 in ethanol(lit.)
Safety DataBack Directory
[Hazard Codes ]

T
[Risk Statements ]

25
[Safety Statements ]

45
[RIDADR ]

UN 2811 6.1/PG 3
[WGK Germany ]

3
Hazard InformationBack Directory
[Chemical Properties]

White Solid
[Uses]

Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells.
[Definition]

ChEBI:(S)-verapamil hydrochloride is a hydrochloride salt resulting from the reaction of equimolar amounts of (S)-verapamil and hydrogen chloride. It is an enantiomer of a dexverapamil hydrochloride.
[Biochem/physiol Actions]

Active enantiomer of (±)-verapamil. Ca2+ channel (L-type) modulator; adrenoceptor antagonist; cardiac depressant.
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