Identification | Back Directory | [Name]
(3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester | [CAS]
35467-43-7 | [Synonyms]
Δ18-Hirsutine delta18-Hirsutine 3-Epicorynantheine delta(Sup 18)-hirsutine 18,19-Didehydrohirsutine methyl (3beta,16E)-16-(methoxymethylidene)coryn-18-en-17-oate (3β,16E)-16,17,18,19-Tetradehydro-17-methoxycorynan-16-carboxylic acid methyl ester (3-beta,16E)-16,17,18,19-Tetradehydro-17-methoxy-corynan-16-carboxylic acid methyl ester Corynan-16-carboxylic acid, 16,17,18,19-tetrahydro-17-methoxy-, methyl ester, (3beta,16E)- Corynan-16-carboxylic acid, 16,17,18,19-tetradehydro-17-methoxy-, methyl ester, (3-beta,16E)- Methyl (E)-2-[(2S,3R,12bR)-3-Ethenyl-1,2,3,4,6,7,12,12B-Octahydroindolo[3,2-h]Quinolizin-2-Yl]-3-Methoxyprop-2-Enoate Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethenyl-1,2,3,4,6,7,12,12b-octahydro-α-(methoxymethylene)-, methyl ester, (αE,2S,3R,12bR)- | [Molecular Formula]
C22H26N2O3 | [MDL Number]
MFCD01731844 | [MOL File]
35467-43-7.mol | [Molecular Weight]
366.46 |
Chemical Properties | Back Directory | [Boiling point ]
533.2±50.0 °C(Predicted) | [density ]
1.22±0.1 g/cm3(Predicted) | [solubility ]
DMSO: soluble | [form ]
A solid | [pka]
18.03±0.60(Predicted) | [color ]
Off-white to yellow |
Hazard Information | Back Directory | [Chemical Properties]
White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Uncaria rhynchophylla (Miq.) Miq. ex Havil. | [Uses]
Hirsuteine can be used for antihypertensive. | [Definition]
ChEBI:Hirsuteine is an alkaloid. | [Biological Activity]
Hirsuteine is an indole alkaloid extracted from Uncaria. It noncompetitively antagonizes nicotine-mediated dopamine release by blocking ion penetration through the nicotinic receptor channel complex. |
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