| Identification | Back Directory | [Name]
7-(2,2-DIMETHYL-5-OXO-4-PHENYL-IMIDAZOLIDIN-1-YL)-3,3-DIMETHYL-6-OXO-2-THIA-5-AZABICYCLO[3.2.0]HEPTANE-4-CARBOXYLIC ACID | [CAS]
3511-16-8 | [Synonyms]
Versapen
Penplenum
Hetacilina
HETACILLIN
Hetacilline
Hetacillinum
phenazacillin
Hetacillin USP/EP/BP
6-(2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl)penicillanic acid
6-[2,2-Dimethyl-5-oxo-4-phenyl-1-imidazolidinyl] penicillanic acid
7-(2,2-DIMETHYL-5-OXO-4-PHENYL-IMIDAZOLIDIN-1-YL)-3,3-DIMETHYL-6-OXO-2-THIA-5-AZABICYCLO[3.2.0]HEPTANE-4-CARBOXYLIC ACID
7-(2,2-DIMETHYL-5-OXO-4-PHENYL-IMIDAZOLIDIN-1-YL)-3,3-DIMETHYL-6-OXO-2-THIA-5-AZABICYCLO[3.2.0]HEPTANE-4-CARBOXYLIC ACID
7-(2,2-DIMETHYL-5-OXO-4-PHENYL-IMIDAZOLIDIN-1-YL)-3,3-DIMETHYL-6-OXO-2-THIA-5-AZABICYCLO[3.2.0]HEPTANE-4-CARBOXYLIC ACID USP/EP/BP
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(4R)-2,2-dimethyl-5-oxo-4-phenyl-1-imidazolidinyl]-3,3-dimethyl-7-oxo-, (2S,5R,6R)- | [EINECS(EC#)]
222-512-5 | [Molecular Formula]
C19H23N3O4S | [MDL Number]
MFCD00056861 | [MOL File]
3511-16-8.mol | [Molecular Weight]
389.47 |
| Chemical Properties | Back Directory | [Melting point ]
189.2-191.0° | [alpha ]
D25 +366° (pyridine) | [Boiling point ]
648.4±55.0 °C(Predicted) | [density ]
1.43±0.1 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly) | [form ]
Solid | [pka]
2.45±0.50(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic, Unstable in Solution |
| Hazard Information | Back Directory | [Originator]
Natacillin,Bristol Banyu,Japan,1970 | [Uses]
Antibacterial. | [Uses]
Hetacillin is a β-lactam antibiotic. | [Definition]
ChEBI:Hetacillin is a penicillin. It has a role as an antibacterial drug. It is a conjugate acid of a hetacillin(1-). | [Manufacturing Process]
To 100 grams of α-aminobenzylpenicillin slurried in 2,500 ml of acetone is
added 200 ml of a 22% solution of potassium ethylhexanoate in dry n-butanol
and the mixture is warmed to 45°C whereupon the acid dissolves. After the
mixture is agitated for 1 hour at 40° to 45°C, the product begins to crystallize
out. Agitation is continued for 4 hours at 45°C after which the product, the
potassium salt of hetacillin, is collected by filtration, washed with 500 ml of
dry acetone, dried for 17 hours at 40°C and found to weigh 70.0 grams. | [Brand name]
Versapen-K (Bristol-Myers Squibb)
. | [Therapeutic Function]
Antibacterial | [storage]
Store at -20°C |
|
| Company Name: |
Musechem
|
| Tel: |
+1-800-259-7612 |
| Website: |
www.musechem.com |
|