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ChemicalBook--->CAS DataBase List--->3484-10-4

3484-10-4

3484-10-4 Structure

3484-10-4 Structure
IdentificationBack Directory
[Name]

2-Methyl-4-nitroindole
[CAS]

3484-10-4
[Synonyms]

2-Methyl-4-nitroindole
2-Methyl-4-nitro-1H-indole
4-Nitro-2-Methyl-1H-indole
1H-Indole, 2-methyl-4-nitro-
[Molecular Formula]

C9H8N2O2
[MDL Number]

MFCD09028445
[MOL File]

3484-10-4.mol
[Molecular Weight]

176.17
Chemical PropertiesBack Directory
[Melting point ]

192-194 °C
[Boiling point ]

365.6±22.0 °C(Predicted)
[density ]

1.355±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[pka]

15.34±0.30(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P280-P271-P261
[Hazard Codes ]

Xi
[HazardClass ]

IRRITANT
[HS Code ]

2933998090
Hazard InformationBack Directory
[Uses]

2-Methyl-4-nitroindole is a useful synthetic intermediate in the synthesis of AZD1981, a CRTH2 receptor antagonist used in patients with moderate to severe COPD. 2-Methyl-4-nitroindole is also used as a reagent in the preparation of anti-angiogenic pyrroloazaflavones.
[Synthesis Reference(s)]

Tetrahedron Letters, 40, p. 5395, 1999 DOI: 10.1016/S0040-4039(99)01014-X
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