| Identification | Back Directory | [Name]
LM22B-10 | [CAS]
342777-54-2 | [Synonyms]
LM22B-10
2,2',2',2'''-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol
Ethanol, 2,2',2'',2'''-[[(4-chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakis-
2-[[4-[[4-[BIS-(2-HYDROXYETHYL)-AMINO]-PHENYL]-(4-CHLORO-PHENYL)-METHYL]-PHENYL]-(2-HYDROXY-ETHYL)-AMINO]-ETHANOL | [Molecular Formula]
C27H33ClN2O4 | [MDL Number]
MFCD00483554 | [MOL File]
342777-54-2.mol | [Molecular Weight]
485.01 |
| Chemical Properties | Back Directory | [Boiling point ]
718.9±60.0 °C(Predicted) | [density ]
1.287±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Store in freezer, under -20°C | [solubility ]
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml | [form ]
A crystalline solid | [pka]
14.00±0.10(Predicted) | [color ]
Light green to green |
| Hazard Information | Back Directory | [Uses]
LM22B-10 is a TrkB and TrkC agonist. Exhibits neurotrophic activity (EC50 = 200-300 nM), improves survival and increases neurite outgrowth in hippocampal cells in vitro. Exhibits no significant activity in a screen of 57 other receptors and transporters. Inhibits binding of BDNF and neurotrophin-3 to TrkB and TrkC, respectively. Active in vivo and brain penetrant. | [storage]
Store at -20°C |
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| Company Name: |
DC Chemicals
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021-58447131 13564518121 |
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http://www.is0513.com/ShowSupplierProductsList927327/0.htm |
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