Identification | Back Directory | [Name]
GLYCOCHOLIC ACID SODIUM SALT HYDRATE | [CAS]
338950-81-5 | [Synonyms]
SODIUM GLYCOCHOLATE HYDRATE SodiumGlycocholateHydrate> N-CHOLYGLYCINE SODIUM SALT HYDRATE GLYCOCHOLIC ACID SODIUM SALT HYDRATE Glycocholic acid hydrate sodiuM salt Glycine, N-[(3α,5β,7α,12α)-3,7,12-trihydroxy-24-oxocholan-24-yl]-, sodium salt, hydrate (1:1:) | [EINECS(EC#)]
212-730-9 | [Molecular Formula]
C26H46NNaO8 | [MDL Number]
MFCD00150466 | [MOL File]
338950-81-5.mol | [Molecular Weight]
523.64 |
Chemical Properties | Back Directory | [Melting point ]
210-215 °C (subl.)(lit.)
| [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
Ethanol (Slightly, Sonicated), DMSO (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White to Off-White | [BRN ]
3854517 |
Hazard Information | Back Directory | [Uses]
Sodium glycocholate hydrate has been used in a study to assess serum total bile acids via a fluorimetric and enzymatic method. It has also been used in a study to investigate its effect on micelle formation and solubilization of testosterone. | [Application]
Sodium glycocholate hydrate is used to determine serum total bile acids by fluorimetric and enzymatic methods. It has also been used in in vitro studies to investigate its effect on micelle formation and solubilization of testosterone. This compound is considered a detergent used to solubilize fats for absorption. This chemical product is synthetically derived from a natural compound, cholic acid. Sodium glycocholate hydrate has been tested in the laboratory for its ability to form a liposomal delivery system to enhance oral insulin delivery. The in vitro results demonstrated that sodium glycocholate liposomes showed promising activity and can be useful to create a new approach to orally deliver insulin more efficiently. | [Definition]
ChEBI: Glycocholic acid sodium salt hydrate is a bile acid glycine conjugate. | [General Description]
Sodium glycocholate hydrate is a conjugated bile salt and an ionic biologic detergent. |
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