| Identification | Back Directory | [Name]
METHYL 1,3-BENZODIOXOL-5-YLACETATE | [CAS]
326-59-0 | [Synonyms]
NSC 105308
ASISCHEM D13375
Methyl 1,3-Benzodioxole-5-acetate
Methyl 1,3-benzodioxol-5-ylacetate
methyl2-(1,3-benzodioxol-5-yl)acetate
Methyl 2-(1,3-dioxaindan-5-yl)acetate
Methyl 4,5-(Methylenedioxy)phenylacetate
Methyl (3,4-Methylenedioxyphenyl)acetate
Methyl 2-(2H-1,3-benzodioxol-5-yl)acetate
1,3-Benzodioxole-5-acetic Acid Methyl Ester
BENZO[1,3]DIOXOL-5-YL-ACETIC ACID METHYL ESTER
[3,4-(Methylenedioxy)phenyl]acetic Acid Methyl Ester
METHYL 1,3-BENZODIOXOL-5-YLACETATE ISO 9001：2015 REACH | [Molecular Formula]
C10H10O4 | [MDL Number]
MFCD08753503 | [MOL File]
326-59-0.mol | [Molecular Weight]
194.18 |
| Chemical Properties | Back Directory | [Boiling point ]
278.3℃ | [density ]
1.265 | [refractive index ]
1.5430 (estimate) | [Fp ]
120.0℃ | [InChI]
InChI=1S/C10H10O4/c1-12-10(11)5-7-2-3-8-9(4-7)14-6-13-8/h2-4H,5-6H2,1H3 | [InChIKey]
HEMYXNDMAAOTCK-UHFFFAOYSA-N | [SMILES]
O1C2=CC=C(CC(OC)=O)C=C2OC1 |
| Hazard Information | Back Directory | [Uses]
Methyl 1,3-benzodioxol-5-ylacetate is a reagent used to prepare pharmaceutically active Benzodioxole derivatives.
| [Preparation]
1,3-Benzodioxole-5-acetic acid methyl ester is a lignan synthesized by the condensation of podophyllotoxin with acetone in the presence of an acid catalyst. | [Mode of action]
1,3-Benzodioxole-5-acetic acid methyl ester is a regioselective inhibitor of 5α→5β conversion. This inhibition leads to a decrease in the production of diene metabolites that may be carcinogenic, as well as a decrease in the production of podophyllotoxin and its derivatives (podophyllum alkaloids). It has been shown to have anti-inflammatory properties and to inhibit prostaglandin synthesis. |
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