Identification | Back Directory | [Name]
mexazolam | [CAS]
31868-18-5 | [Synonyms]
Melex CS 386 Sedoxil mexazolam mexazolam API mexazolam USP/EP/BP Mexazolam (1.0mg/ml in Acetonitrile) MexazolamQ: What is
Mexazolam Q: What is the CAS Number of
Mexazolam 10-Chloro-2,3,7,11b-tetrahydro-3-methyl-11b-(o-chlorophenyl)oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one 10-chloro-11b-(2-chlorophenyl)-3-methyl-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one 10-Chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one 10-Chloro-11b-(o-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one Oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one, 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyl- Oxazolo[3,2-d][1,4]benzodiazepin-6(5H)-one, 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyl- (9CI) | [Molecular Formula]
C18H16Cl2N2O2 | [MDL Number]
MFCD00866982 | [MOL File]
31868-18-5.mol | [Molecular Weight]
363.24 |
Chemical Properties | Back Directory | [Melting point ]
172-175° | [Boiling point ]
522.2±50.0 °C(Predicted) | [density ]
1.3817 (rough estimate) | [refractive index ]
1.6100 (estimate) | [pka]
6.69(at 25℃) |
Hazard Information | Back Directory | [Description]
Mexazolam is a benzodiazepine anxiolytic closely related to flutazolam. It is
reported to be particularly effective against psychosomatic essential hypertension,
peptic ulcer, irritable colon and autonomic dystonia. | [Originator]
Sankyo (Japan) | [Uses]
Mexazolam is a benzodiazepine derivative and have been investigated for its therapeutic value in treating anxiety. Mexazolam is known to be metabolized via the CYP3A4 pathway. | [Definition]
ChEBI: Mexazolam is an oxazolobenzodiazepine and a hemiaminal ether. | [Brand name]
MELEX |
Safety Data | Back Directory | [Toxicity]
LD50 in male, female mice; male, female rats (mg/kg): 4687, 4571, 810, 4500 orally; >6000, >6000, >4000, >4000 i.p. or s.c. (Masuda) |
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