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ChemicalBook--->CAS DataBase List--->30924-31-3

30924-31-3

30924-31-3 Structure

30924-31-3 Structure
IdentificationBack Directory
[Name]

cafaminol
[CAS]

30924-31-3
[Synonyms]

cafaminol
Cafaminolum
Mecoffaminum
Methylcoffanolamin
Methylcoffanolamine
3,7-Dihydro-8-[(2-hydroxyethyl)methylamino]-1,3,7-trimethyl-1H-purine-2,6-dione
1H-Purine-2,6-dione, 3,7-dihydro-8-[(2-hydroxyethyl)methylamino]-1,3,7-trimethyl-
[EINECS(EC#)]

250-390-3
[Molecular Formula]

C11H17N5O3
[MDL Number]

MFCD00867734
[MOL File]

30924-31-3.mol
[Molecular Weight]

267.28
Chemical PropertiesBack Directory
[Melting point ]

162-164°
Hazard InformationBack Directory
[Originator]

Rhinoptil,Promonta,W. Germany,1974
[Definition]

ChEBI: Cafaminol is an oxopurine.
[Manufacturing Process]

21 g 8-chlorocaffeine and 15 g beta-N-methylaminoethanol are heated to 140°-160°C for 30 minutes. Then the temperature is increased for 15-20 minutes to 165°-170°C. On cooling a colorless mass of crystals results. This is boiled with 50-60 ml ethanol and crystallized. Colorless crystals result which are soluble in water up to about 6%; pH of the aqueous solution is 6.9. The yield is 19 g while the MP is 162°-164°C.
[Therapeutic Function]

Nasal decongestant
Safety DataBack Directory
[Toxicity]

LD50 s.c. in male mice: 700 mg/kg (Klosa)
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