| Identification | Back Directory | [Name]
N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine | [CAS]
300842-64-2 | [Synonyms]
Acc-789
ZK 202650
NVP-ACC-789
ACC-789 (NVP-ACC789)
ACC-789; ZK-202650; NVP-ACC-789;ACC789;ACC 789
N-(3-Bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine
N-(3-Bromo-4-methylphenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine | [Molecular Formula]
C21H17BrN4 | [MDL Number]
MFCD17014834 | [MOL File]
300842-64-2.mol | [Molecular Weight]
405.29 |
| Chemical Properties | Back Directory | [Boiling point ]
607.7±55.0 °C(Predicted) | [density ]
1.441 | [storage temp. ]
Store at -20°C | [solubility ]
DMSO:13.0(Max Conc. mg/mL);32.08(Max Conc. mM)
DMF:0.5(Max Conc. mg/mL);1.23(Max Conc. mM)
DMF:PBS (pH 7) (1:10):0.09(Max Conc. mg/mL);0.22(Max Conc. mM)
Ethanol:0.2(Max Conc. mg/mL);0.49(Max Conc. mM) | [form ]
A crystalline solid | [pka]
5.46±0.10(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
NVP-ACC789, is an inhibitor of human VEGFR-1, VEGFR-2 (mouse VEGFR-2), VEGFR-3 and PDGFR-β with IC50s of 0.38, 0.02 (0.23), 0.18, 1.4 μM, respectively. |
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D&C Chemicals
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