| Identification | Back Directory | [Name]
1,2,3,4-TETRAHYDRO-2-NAPHTHYLAMINE | [CAS]
2954-50-9 | [Synonyms]
2954-50-9
aminotetralin
2-aminotetralin
2-AT (2-AMinotetralin)
2-tetralinamine hydrobromide
beta-tetrahydronaphthylamine
tetralin-2-amine hydrobromide
tetrahydro-beta-naphthylamine
tetralin-2-ylamine hydrobromide
1,2,3,4-tetrahydro-2-naphthylamin
2-amino-1,2,3,4-tetrahydronaftalen
1,2,3,4-TETRAHYDRO-2-NAPHTHYLAMINE
1,2,3,4-TETRAHYDRONAPHTHALEN-2-AMINE
2-NaphthylaMine, 1,2,3,4-tetrahydro-
1,2,3,4-Tetrahydro-2-naphthalenamine
beta-1,2,3,4-tetrahydronaphthylamine
1,2,3,4-Tetrahydronaphthalene-2-amine
1,2,3,4-Tetrahydro-phthalen-2-ylamine
2-NAPHTHALENAMINE, 1,2,3,4-TETRAHYDRO-
1,2,3,4-Tetrahydro-naphthalen-2-ylaMine
1,2,3,4-Tetrahydronaphthalen-2-amine (>80%)
1,2,3,4-tetrahydronaphthalen-2-amine hydrobromide
1,2,3,4-tetrahydro-2-naphthalenamine(SALTDATA: FREE) | [EINECS(EC#)]
220-973-7 | [Molecular Formula]
C10H13N | [MDL Number]
MFCD00045577 | [MOL File]
2954-50-9.mol | [Molecular Weight]
147.22 |
| Chemical Properties | Back Directory | [Melting point ]
149-151 °C | [Boiling point ]
257.35°C (rough estimate) | [density ]
1.0048 (rough estimate) | [refractive index ]
1.5620 (estimate) | [RTECS ]
QM4900000 | [storage temp. ]
Refrigerator, under inert atmosphere | [solubility ]
Chloroform (Soluble, Sonicated), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
10.50±0.20(Predicted) | [color ]
Dark Yellow to Very Dark Brown |
| Safety Data | Back Directory | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36/37/39 | [Toxicity]
dog,LDLo,intravenous,10mg/kg (10mg/kg),GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDSVASCULAR: REGIONAL OR GENERAL ARTERIOLAR CONSTRICTIONSENSE ORGANS AND SPECIAL SENSES: MYDRIASIS (PUPILLARY DILATION): EYE,Archives Internationales de Pharmacodynamie et de Therapie. Vol. 35, Pg. 70, 1928. |
| Hazard Information | Back Directory | [Uses]
1,2,3,4-Tetrahydronaphthalen-2-amine is a useful reagent for the preparation of N-heteroaryl-tetrahydrocarbazolamines as AHR inhibitors. | [Definition]
ChEBI: 1,2,3,4-tetrahydronaphthalen-2-amine is a member of tetralins. | [Synthesis Reference(s)]
Organic Syntheses, Coll. Vol. 1, p. 499, 1941
The Journal of Organic Chemistry, 68, p. 7618, 2003 DOI: 10.1021/jo030053+ | [Enzyme inhibitor]
This conformationally constrained cyclohexylamine (FW = 147.22 g/mol;
CAS 2954-50-9, 1743-01-7 (HCl), 21880-87-5 (S-isomer), 21966-60-9 (R-
isomer) ), also called b-tetrahydronaphthylamine, and its many derivatives
are inhibitors of serotonin and norepinephrine transport and likely induces
their release as well. Target (s) : monamine oxidase, or amine oxidase;
5-hydroxytryptamine transport; norepinephrine transport;
phenylethanolamine N-methyltransferase. |
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