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ChemicalBook--->CAS DataBase List--->28608-75-5

28608-75-5

28608-75-5 Structure

28608-75-5 Structure
IdentificationBack Directory
[Name]

ORIENTIN
[CAS]

28608-75-5
[Synonyms]

lutexin
ORIENTIN
ORIENTINE
Polygonin
Aids026706
Aids-026706
ORIENTIN(P)
ORIENTIN(SH)
ORIDONIN (RG)
Orientin,Lutexin
orientin(flavone)
8-Glucosylluteolin
ORIENTIN WITH HPLC
ORIENTIN USP/EP/BP
luteolin8-glucoside
LUTEOLIN-8-C-GLUCOSIDE
Luteolin 8-C-β-D-glucopyranoside
Orientin, froM PolygonuM orientale
Luteolin 8-C-beta-D-Glucopyranoside
Orientin, 98%, from Polygonum orientale
Orientin, 98%, from Polygonum orientale L.
8-β-D-Glucopyranosyl-3',4',5,7-tetrahydroxyflavone
8-beta-D-Glucopyranosyl-3',4',5,7-tetrahydroxyflavone
2-(3,4-dihydroxyphenyl)-8-beta-d-glucopyranosyl-5,7-dihydroxy-4h-1-benzopyra
4h-1-benzopyran-4-one,2-(3,4-dihydroxyphenyl)-8-beta-d-glucopyranosyl-5,7-dihy
2-(3,4-Dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-(β-D-glucopyranosyl)-4H-1-benzopyran-4-one
2-(3,4-Dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-.beta.-D-glucopyranosyl-5,7-dihydroxy-
[Molecular Formula]

C21H20O11
[MDL Number]

MFCD00017432
[MOL File]

28608-75-5.mol
[Molecular Weight]

448.38
Chemical PropertiesBack Directory
[Melting point ]

260-285°C
[Boiling point ]

816.1±65.0 °C(Predicted)
[density ]

1.759±0.06 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Sealed in dry,2-8°C
[solubility ]

1 M NaOH: soluble1mg/mL, clear, yellow-orange
[form ]

powder
[pka]

6.24±0.40(Predicted)
[color ]

yellow
[Stability:]

Hygroscopic
[LogP]

1.580 (est)
Safety DataBack Directory
[Safety Statements ]

24/25
[WGK Germany ]

3
[RTECS ]

DJ3009300
[HS Code ]

29389090
Hazard InformationBack Directory
[Description]

Orientin is a flavone glycoside originally isolated from P. orientale that has diverse biological activities, including antioxidant, antibacterial, and anti-inflammatory properties. Orientin scavenges 2,2-diphenyl-1-picryl-hydrazyl (DPPH; Item No. 14805) radicals with an IC50 value of 316.21 μg/ml. It also decreases the cytopathic effects of parainfluenza type 3 virus with an IC50 value of 11.7 μg/ml and a cytotoxic concentration (CC50) value of 375 μg/ml in Hep-2 cells. Orientin (5-40 μM) inhibits LPS-induced barrier disruption, decreases the expression of toll-like receptor 4 (TLR4), phosphorylated p38, and NF-κB, and decreases TNF-α production and IL-6 secretion in a dose-dependent manner in human umbilical vein endothelial cells (HUVECs). It also prolongs survival in a mouse model of LPS-induced lethal endotoxemia when administered at a dose of 36 μg/animal 12 hours after LPS administration.
[Chemical Properties]

Yellow powder
[Uses]

Orientin is a flavone, a chemical flavonoid compound. Orientin have been investigated for its anti-oxidant, antihypertensive and antihyperlipidemic effects.
[Definition]

ChEBI: A C-glycosyl compound that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 8.
Spectrum DetailBack Directory
[Spectrum Detail]

ORIENTIN(28608-75-5)IR1
ORIENTIN(28608-75-5)IR2
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