Identification | Back Directory | [Name]
10-formyldihydrofolate | [CAS]
28459-40-7 | [Synonyms]
C20H21N7O7 10-ForMyl-7 Folic acid IMpurity F Folinic Acid IMpurity F 10-formyldihydrofolic acid Folinic Acid EP Impurity F Levofolinate EP Impurity F Impurity F of Calcium Levofolinate 10-Formyl-7,8-dihydro Folic Acid Disodium Salt 10-ForMyl-7,8-dihydro Folic Acid (>85%) DisodiuM Salt L-Glutamic acid,N-[4-[[(2-amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]formylamino]benzoyl]- | [Molecular Formula]
C20H21N7O7 | [MOL File]
28459-40-7.mol | [Molecular Weight]
471.43 |
Hazard Information | Back Directory | [Uses]
10-Formyl-7,8-dihydrofolic acid is a novel folate found in methotrexate-treated cells. 10-Formyldihydrofolate (H2folate) has not been found as a component of intracellular folates in normal tissues but has been identified in the cytosol of methotrexate (MTX)-treated MCF-7 breast cancer cells and normal human myeloid precursor cells. | [Definition]
ChEBI:10-formyldihydrofolic acid is the 10-formyl derivative of dihydrofolic acid. It is a conjugate acid of a 10-formyldihydrofolate(2-). |
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