| Identification | Back Directory | [Name]
PICROSIDE I | [CAS]
27409-30-9 | [Synonyms]
PICROSIDE I
Picroside-Ⅰ
AMphicoside I
Amphicoside Ⅰ
PICOLINIC ACID(P)
Other Cas No, 76248-14-1
β-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-
Picroside I, 98%, from Picrorhiza scrophulariiflora Pennel
6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl,6-(3-phenyl-2-propenoate), [1aS-[1aα,1bβ,2β(E),5aβ,6β,6aα]]-
(1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl-β-D-glucopyranoside 6-[(2E)-3-phenyl-2-propenoate]
β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-[(2E)-3-phenyl-2-propenoate]
(1aS,1bS,2S,5aR,6S,6aS)-6-Hydroxy-1a-(hydroxymethyl)-1a,1b,2,5a,6,6a-hexahydrooxireno[4,5]cyclopenta[1,2-c]pyran-2-yl 6-O-[(2E)-3-phenyl-2-propenoyl]-beta-D-glucopyranoside
β-d-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-(3-phenyl-2-propenoate), [1aS-[1aα,1bβ,2β(E),5aβ,6β,6aα]]-
[1aS-[1aalpha,1bbeta,2beta(E),5abeta,6beta,6aalpha]]-1a,1b,2,5a,6,6a-Hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl 6-(3-phenyl-2-propenoate) beta-D-glucopyranoside
beta-d-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl, 6-(3-phenyl-2-propenoate), [1aS-[1aalpha,1bbeta,2beta(E),5abeta,6beta,6aalpha]]- | [EINECS(EC#)]
248-445-1 | [Molecular Formula]
C24H28O11 | [MDL Number]
MFCD00017720 | [MOL File]
27409-30-9.mol | [Molecular Weight]
492.47 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
ethanol: soluble1mg/mL, clear, colorless | [form ]
powder | [color ]
White | [InChIKey]
BSYHSWKTXMTFNF-NTLZGZQOSA-N |
| Hazard Information | Back Directory | [Description]
Picroliv is a hepatoprotective mixture of compounds that is isolated from an herb native to the Himalayas.1 Picroside I is an iridoid glycoside found in picroliv.1 By itself, picroside I blocks changes in acid phosphatase activity, phospholipid levels, and lipid peroxide production induced by D-galactosamine in rat liver.2 Picroside I also enhances neurite outgrowth in PC12D cells induced by basic fibroblast growth factor and 7S nerve growth factor when given at 60 μM.3,4 At concentrations as low as 5 μM, picroside I enhances the ATPase activity of the efflux transporter P-glycoprotein.5 | [Uses]
Picroside I acts as an oxygen free radical scavenger and thus promotes anti-inflammatory activity and may be used in the treatment of arthritis. |
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